- Tattoo on right arm symbolizing his film "When in Rome" with Mary-kate and Ashley Olsen.
- Has a daughter Tyler Jade Nixon, born May 29th, 2007.
- Friend of San Antonio native Actor Jared Padalecki.
- Dated actress Haylie Duff.
- Derek left home to start a career in acting at 18
- Got his tooth chipped by Gary Busey on Gary's 1st day of filming on the movie Hallettsville.
- Just finished filming the movie Hallettsville with close friends director Andrew Pozza & fellow actor Jordan Brower both native San Antonians
- Screen tested for "Eurotrip" (2004) but the director chose Scott Mechlowicz for the part of Scotty.
- Went to North East School of the Arts High School in San Antonio, Texas with fellow film actor Eric Jungmann and Broadway actor Curtis Holbrook.
- Dated actress Skyler Shaye.
- Back in Burbank, Califoria working with his two completed feature films (Hallettsville, and The Lights). (January 2007)
- In production on Be My Teacher (2009), playing Evan alongside 'LaTeace Towns' (March 2009)
- Austin, Texas on Alexander Shumake's Killer School Girls from Outer Space (June 2009)
- Producing Horror film called "Hallettsville" in which he will be starring along with Logan Brown. (March 2004)
- Shooting "The Lights" starring Joe Estevez & Derek Lee Nixon at Ranch Studios in Kyle, Texas. (November 2006)
- In Geogia & North Carolina starring in and producing Outrage. (May 2007)
- Celebrated the birth of his daughter Tyler Jade Nixon (May 2007)
- In Production on The Jerk Theory (2008), playing Chester who is the quintessential nice guy and lead guitarist of the band alongside Josh Henderson, Jenna Dewan and Tom Arnold with cameo appearances from Danny Bonnaducci and Todd Bridges (January 2008)
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