- Younger half brother of Livan Hernández, who defected from Cuba in 1995 and signed with the Florida Marlins.
- Has two daughters, Yahumara Hernández Manzo (15 March 1990) and Stheffi Hernández Manzo (15 July 1995) by ex-wife, Norma Elvira Manzo Ibanez.
- Although he told the media when he arrived in New York that he was born in 1969, Hernández's divorce papers from Norma Elvira Manzo Ibanez revealed that he was born in 1965.
- Was working as a physical therapist at a mental hospital when he defected with seven others, including his now-wife, Nora, on 26 December 1997.
- Posted a 53-38 record with a 4.04 ERA in five seasons with the New York Yankees.
- Was 129-47 for the Cuban national team.
- Agreed to a one-year contract with the Montreal Expos for $4.1 million. (February 10, 2003)
- The New York Yankees sent Hernández and $2 million to the Chicago White Sox for P Antonio Osuna and minor league pitcher Delvis Lantigua. The White Sox then sent Hernández, P Rocky Biddle, outfielder Jeff Liefer and cash to the Montreal Expos for P Bartolo Colón and minor league infielder Jorge Nunez. (January 15, 2003)
- Made major league debut on 3 June 1998.
- Named to Baseball Digest magazine's 1998 Rookie All-Star Team.
- (December 14) Traded to the Arizona Diamondbacks. (2005)
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