- Wynn's yearly salary was said to be more than $30 million in 1998, among the largest in the U.S.
- Born in New Haven, Stephen Wynn grew up in Utica, New York. His father, Michael Weinberg, changed the family name to Wynn.
- In 1971, when he was 29 years old, Wynn was diagnosed with retinitis pigmentosa, an incurable, inherited disease that causes its victims to gradually go blind. He founded, in his father's memory, the Michael M. Wynn Center for Inherited Retinal Diseases at the John Moran Eye Center at the University of Utah.
- Longtime personal friend of Frank Sinatra and Donald Trump.
- Chairman and CEO of Mirage Resorts Inc., executive of three of the largest and most successful hotel-casinos in the world - Las Vegas's Mirage, Treasure Island, and Bellagio.
- Father, with ex-wife Elaine Wynn, of two adult daughters, Kevyn Wynn, and Gillian Wynn, who also work for Mirage Resorts Inc.
- Married Andrea Hissom at the Wynn Las Vegas Chapel on April 30, 2011. Clint Eastwood served as best man.
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