- Son of Tom Trimble and Gail Trimble.
- First cousin once removed of Lee Donham
- 4th cousin twice removed of Clarence Nash, the voice of Donald Duck. Both are descended from the Revolutionary War sergeant George Brown (1760-1825)
- Older brother of Daniel Trimble.
- Graduated from U.C. Berkeley in May 1999 with a major in Anthropology (Archaeology), and minors in both Dramatic Arts (Theater & Acting) and Scandinavian (Mythology & History). He worked as a Health Worker at Freeborn Hall, a Resident Assistant at Spens-Black Hall, and a Resident Assistant back at Freeborn Hall.
- Nephew of Paul C. Trimble.
- Step-Grandson of Harold Yager.
- Great-Grandnephew of Charles Darnton.
- Half 1st Cousin of Tim Harrison and his wife Donna Harrison. Half 1st Cousin Once Removed of Jessie Harrison and Kellie Harrison, and Step Half 1st Cousin Once Removed of Chris Patton and Kevin Patton.
- Went to college with Brianna Keilar, Jeff Cohen, Alexandre Chen, Amir Talai, Kenny Byerly, Tracy Zugnoni, Adrianna Granville, and Daniel Granville. Went to high school with Roberto Schein, Nicole Kristal, and Erik Roner. Went to middle school with Julie Warnock.
- No known relation to Richie Trimble, despite the fact that they've worked together.
- 3rd cousin of Jonathan Williams. Both are descended from William Trimble (1802-1888).
- 2nd cousin once removed of Nicole Souza. Both are descended from Melvin Roy Donham (1884-1960).
- 9th cousin of Barack Obama. Both are descended from Jonathan Singletary Dunham (1640-1724).
- 2nd cousin once removed of Joan Trimble. Both are descended from William Trimble (1802-1888).
- Scott Trimble and Mindi Trimble are the parents of twins: James Tiberius Simpson Trimble VI and Theodore Rex Sinclair Trimble Esq.
- 2nd cousin thrice removed of book author Dorothea Castelhun Bassett (1889-1950), the sister-in-law of esteemed film composer R.H. Bassett. Both are descended from Friedrich Karl Castelhun (1764-1836) and Louise Krück Castelhun (1770-1827). Scott Trimble and R.H. Bassett also happen to be 9th cousins thrice removed via Mayflower passenger Edward Fuller (1575-1621).
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