- Daughter of Luiz Eduardo Osório Negrini, an engineer, and wife Neusa Vidal de Negreiros, a pedagogue, a descendant of André Vidal de Negreiros (b. Paraíba, 1606, d. Goiana, 3 Feb 1680), Governor of Maranhão (11 May 1655 - 23 Sep 1656), Governor of Pernambuco (1657 - Sep 1661 and 1667) and Governor and Captain-General of Angola (1661 - 1666).
- Alessandra's husband is Otto Maximiliano Pereira de Cordeiro Ferreira, born on June 28th 1968 in Belo Jardim, Brazil.
- Her ex-husband, singer and composer Otto, had Negrinis's nickname ("Ale") tattooed on his arm.
- Her son Antônio Benício, whose father is Murilo Benício, was born on 16th December 1996, in São Paulo, São Paulo, Brazil.
- Daughter, with Otto, Betina, born on 29 September 2004 in Rio de Janeiro, RJ, Brazil.
- Posed for Brazilian Playboy on Abril 2000.
- Husband Otto is a very respected musician from Recife, capital of Pernambuco (a Brazil's State), being a former percussionist from the groups Chico Science & Nação Zumbi (currently just Nação Zumbi after their leader's death) and Mundo Livre S/A.
- Has a brother named Paulo Roberto Vidal de Negreiros Negrini.
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