- When Pat Buttram particularly enjoyed something, he was known to remark, "That was more fun that being on location with Mary Beth Hughes!" Pat and Mary Beth worked together on Riders in the Sky (1949).
- Had five husbands.
- Was TV's first celebrity weather girl, "The Weather Miss," for Los Angeles station KTLA from 1953-1954.
- Later on in life, she worked as a telemarketer for Sprint.
- Despite being a cult favorite, she will probably be remembered best for her role in the outrageously campy I Accuse My Parents (1944), which was later used as cannon fodder for Mystery Science Theater 3000 (1988).
- She had one child, Donald North, who is a professional scuba diver and sells underwater equipment.
- Was a natural redhead, but is best known as a platinum blonde.
- She has appeared in two films that have been selected for the National Film Registry by the Library of Congress as being "culturally, historically or aesthetically" significant: The Women (1939) and The Ox-Bow Incident (1942).
- She was in two episodes of Mystery Science Theater 3000 (1988). There was her more memorable performance in I Accuse My Parents (1944) but she was also in Last of the Wild Horses (1948).
- Upon her death, she was cremated and her ashes returned to her son.
- In 1975 she was attending a Cosmetology School in Reseda, CA.
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