Sean Hayes, Leslie Mann, Kristen Bell, and Kenan Thompson

Jeff Goldblum and Leslie Mann in Perfume (2001)

Leslie Mann, Steve Carell, Janelle Monáe, and Gwendoline Christie in Welcome to Marwen (2018)

Leslie Mann, Merritt Wever, Eiza González, and Gwendoline Christie in Welcome to Marwen (2018)

Leslie Mann and Ike Barinholtz in Blockers (2018)

Leslie Mann, Ike Barinholtz, and John Cena in Blockers (2018)

Leslie Mann and Seth Meyers in Late Night with Seth Meyers (2014)

Robert De Niro and Leslie Mann in The Comedian (2016)

Leslie Mann and Judd Apatow in Conan (2010)

Leslie Mann, Dakota Johnson, and Rebel Wilson in How to Be Single (2016)

Leslie Mann and Jake Lacy in How to Be Single (2016)

Leslie Mann and Dakota Johnson in How to Be Single (2016)

Brad Garrett, Leslie Mann, and Cooper Raiff in Cha Cha Real Smooth (2022)

Leslie Mann, Pedro Pascal, and Iris Apatow in The Bubble (2022)

David Duchovny, Leslie Mann, Pedro Pascal, Keegan-Michael Key, Karen Gillan, Iris Apatow, Ben Ashenden, Alexander Owen, and Guz Khan in The Bubble (2022)

David Duchovny, Leslie Mann, and Pedro Pascal in The Bubble (2022)

Albert Brooks, John Lithgow, Leslie Mann, Melissa McCarthy, Paul Rudd, and Jason Segel in This Is 40 (2012)

Adam Sandler, Leslie Mann, and Seth Rogen in Funny People (2009)

Jason Lee, Leslie Mann, Megan Mullally, Tammy Blanchard, and Tom Green in Stealing Harvard (2002)