Catherine O'Hara, Eugene Levy, Annie Murphy, and Dan Levy in Schitt's Creek (2015)

Catherine O'Hara, Annie Murphy, and Dan Levy in Schitt's Creek (2015)

Catherine O'Hara in Tales from the Crypt (1989)

Catherine O'Hara and Ryan Kwanten in The Right Kind of Wrong (2013)

Catherine O'Hara, Adam Scott, and Richard Jenkins in A.C.O.D. (2013)

Catherine O'Hara, Jane Krakowski, and Bryan Cranston in 30 Rock (2006)

Catherine O'Hara, Bryan Cranston, and Jack McBrayer in 30 Rock (2006)

Catherine O'Hara and Bryan Cranston in 30 Rock (2006)

Catherine O'Hara and Fred Willard in Waiting for Guffman (1996)

Parker Posey, Christopher Guest, Catherine O'Hara, Eugene Levy, and Fred Willard in Waiting for Guffman (1996)

Parker Posey, Lewis Arquette, Bob Balaban, Christopher Guest, Catherine O'Hara, Matt Keeslar, Eugene Levy, and Fred Willard in Waiting for Guffman (1996)

Katherine Heigl and Catherine O'Hara in Killers (2010)

Jim Carrey, Catherine O'Hara, Jane Adams, and Jennifer Coolidge in A Series of Unfortunate Events (2004)

Claire Danes and Catherine O'Hara in Temple Grandin (2010)

Catherine O'Hara, Schuyler Fisk, Colin Hanks, Garry Marshall, and Dana Ivey in Orange County (2002)

Catherine O'Hara and Pedro Pascal in Future Days (2025)

Catherine O'Hara and Seth Rogen in The Studio (2025)

Winona Ryder, Catherine O'Hara, and Jenna Ortega in Beetlejuice Beetlejuice (2024)

Catherine O'Hara in Saturday Night Live (1975)

Parker Posey, Christopher Guest, Catherine O'Hara, Michael Hitchcock, Doane Gregory, John Michael Higgins, Eugene Levy, and Michael McKean

Catherine O'Hara and Eugene Levy in Best in Show (2000)

Catherine O'Hara in Beetlejuice Beetlejuice (2024)

Winona Ryder, Catherine O'Hara, Justin Theroux, and Jenna Ortega in Beetlejuice Beetlejuice (2024)

Catherine O'Hara and Bryan Cranston in Watch What Happens Live with Andy Cohen (2009)

Catherine O'Hara and Emily Blunt in Pain Hustlers (2023)

Catherine O'Hara and Eugene Levy in A Mighty Wind (2003)

Michael Keaton and Catherine O'Hara in Game 6 (2005)

Catherine O'Hara at an event for The Wild Robot (2024)

J.T. Walsh, Christine Lahti, Catherine O'Hara, Jena Malone, and Jeffrey D. Sams in Hope (1997)

Jeff Daniels, Hector Elizondo, and Catherine O'Hara in There Goes the Neighborhood (1992)

Jeff Daniels and Catherine O'Hara in There Goes the Neighborhood (1992)

Christina Ricci, Gabriel Byrne, Jared Leto, Catherine O'Hara, and Emily Mortimer in The Last of the High Kings (1996)

Parker Posey, Christopher Guest, Catherine O'Hara, Jennifer Coolidge, John Michael Higgins, Eugene Levy, Jane Lynch, and Michael McKean in Waiting for Guffman (1996)