Andie MacDowell, Laura San Giacomo, James Spader, and Peter Gallagher in Sex, Lies, and Videotape (1989)

Molly Ringwald, Rob Lowe, Laura San Giacomo, Gary Sinise, Kareem Abdul-Jabbar, Ruby Dee, Corin Nemec, and Bill Fagerbakke in The Stand (1994)

Laura San Giacomo in Sex, Lies, and Videotape (1989)

Laura San Giacomo, Annabella Sciorra, and Jane Kaczmarek in Jenifer (2001)

Laura San Giacomo, Sandra Bernhard, Cameron Dye, Matt McCoy, and Frank Zagarino in The Apocalypse (1997)

Laura San Giacomo, George Segal, Wendie Malick, David Spade, and Enrico Colantoni in Just Shoot Me! (1997)

Christopher Lloyd, Laura San Giacomo, Lea Thompson, Patrick Dempsey, Amanda Plummer, Judge Reinhold, Fisher Stevens, LL Cool J, Robert Loggia, and Carl Reiner in The Right to Remain Silent (1996)

Laura San Giacomo in Least Among Saints (2012)

Laura San Giacomo, Charles S. Dutton, Azura Skye, A.J. Cook, Martin Papazian, Audrey Marie Anderson, and Tristan Lake Leabu in Least Among Saints (2012)

Laura San Giacomo in Nina Takes a Lover (1994)

Laura San Giacomo and Tom Selleck in Quigley Down Under (1990)

Laura San Giacomo, Henry Winkler, and Fred Melamed in starting now (2022)

Laura San Giacomo in crazytimesh*tshow (2022)

Laura San Giacomo and George Segal in Just Shoot Me! (1997)

Laura San Giacomo in Just Shoot Me! (1997)

Laura San Giacomo and David Spade in Just Shoot Me! (1997)

Laura San Giacomo and Enrico Colantoni in Just Shoot Me! (1997)

Laura San Giacomo and Wendie Malick in Just Shoot Me! (1997)

Laura San Giacomo and Rebecca Romijn in Just Shoot Me! (1997)

Laura San Giacomo and Peter Gallagher in Sex, Lies, and Videotape (1989)

Laura San Giacomo and James Spader in Sex, Lies, and Videotape (1989)

Laura San Giacomo and Chris Hogan in Just Shoot Me! (1997)

Laura San Giacomo, Sandra Bernhard, Cameron Dye, and Frank Zagarino in The Apocalypse (1997)