On a journey to find the cure for a Tatarigami's curse, Ashitaka finds himself in the middle of a war between the forest gods and Tatara, a mining colony. In this quest he also meets San, the Mononoke Hime.
A young witch, on her mandatory year of independent life, finds fitting into a new community difficult while she supports herself by running an air courier service.
During her family's move to the suburbs, a sullen 10-year-old girl wanders into a world ruled by gods, witches and spirits, and where humans are changed into beasts.