ranking the actors to play batman

Christian Charles Philip Bale was born in Pembrokeshire, Wales, UK on January 30, 1974, to English parents Jennifer "Jenny" (James) and David Bale. His mother was a circus performer and his father, who was born in South Africa, was a commercial pilot. The family lived in different countries throughout Bale's childhood, including England, Portugal, and the United States. Bale acknowledges the constant change was one of the influences on his career choice.

His first acting job was a cereal commercial in 1983; amazingly, the next year, he debuted on the West End stage in "The Nerd". A role in the 1986 NBC mini-series Anastasia: The Mystery of Anna (1986) caught Steven Spielberg's eye, leading to Bale's well-documented role in Empire of the Sun (1987). For the range of emotions he displayed as the star of the war epic, he earned a special award by the National Board of Review for Best Performance by a Juvenile Actor.

Adjusting to fame and his difficulties with attention (he thought about quitting acting early on), Bale appeared in Kenneth Branagh's 1989 adaptation of Shakespeare's Henry V (1989) and starred as Jim Hawkins in a TV movie version of Treasure Island (1990). Bale worked consistently through the 1990s, acting and singing in Newsies (1992), Swing Kids (1993), Little Women (1994), The Portrait of a Lady (1996), The Secret Agent (1996), Metroland (1997), Velvet Goldmine (1998), All the Little Animals (1998), and A Midsummer Night's Dream (1999). Toward the end of the decade, with the rise of the Internet, Bale found himself becoming one of the most popular online celebrities around, though he, with a couple notable exceptions, maintained a private, tabloid-free mystique.

Bale roared into the next decade with a lead role in American Psycho (2000), director Mary Harron's adaptation of the controversial Bret Easton Ellis novel. In the film, Bale played a murderous Wall Street executive obsessed with his own physicality - a trait for which Bale would become a specialist. Subsequently, the 10th Anniversary issue for "Entertainment Weekly" crowned Bale one of the "Top 8 Most Powerful Cult Figures" of the past decade, citing his cult status on the Internet. EW also called Bale one of the "Most Creative People in Entertainment", and "Premiere" lauded him as one of the "Hottest Leading Men Under 30".

Bale was truly on the Hollywood radar at this time, and he turned in a range of performances in the remake Shaft (2000), Captain Corelli's Mandolin (2001), the balmy Laurel Canyon (2002), and Reign of Fire (2002), a dragons-and-magic commercial misfire that has its share of defenders.

Two more cult films followed: Equilibrium (2002) and The Machinist (2004), the latter of which gained attention mainly due to Bale's physical transformation - he dropped a reported 60+ pounds for the role of a lathe operator with a secret that causes him to suffer from insomnia for over a year.

Bale's abilities to transform his body and to disappear into a character influenced the decision to cast him in Batman Begins (2005), the first chapter in Christopher Nolan's definitive trilogy that proved a dark-themed narrative could resonate with audiences worldwide. The film also resurrected a character that had been shelved by Warner Bros. after a series of demising returns, capped off by the commercial and critical failure of Batman & Robin (1997). A quiet, personal victory for Bale: he accepted the role after the passing of his father in late 2003, an event that caused him to question whether he would continue performing.

Bale segued into two indie features in the wake of Batman's phenomenal success: The New World (2005) and Harsh Times (2005). He continued working with respected independent directors in 2006's Rescue Dawn (2006), Werner Herzog's feature version of his earlier, Emmy-nominated documentary, Little Dieter Needs to Fly (1997). Leading up to the second Batman film, Bale starred in The Prestige (2006), the remake of 3:10 to Yuma (2007), and a reunion with director Todd Haynes in the experimental Bob Dylan biography, I'm Not There (2007).

Anticipation for The Dark Knight (2008) was spun into unexpected heights with the tragic passing of Heath Ledger, whose performance as The Joker became the highlight of the sequel. Bale's graceful statements to the press reminded us of the days of the refined Hollywood star as the second installment exceeded the box-office performance of its predecessor.

Bale's next role was the eyebrow-raising decision to take over the role of John Connor in the Schwarzenegger-less Terminator Salvation (2009), followed by a turn as federal agent Melvin Purvis in Michael Mann's Public Enemies (2009). Both films were hits but not the blockbusters they were expected to be.

For all his acclaim and box-office triumphs, Bale would earn his first Oscar in 2011 in the wake of The Fighter (2010)'s critical and commercial success. Bale earned the Best Supporting Actor award for his portrayal of Dicky Eklund, brother to and trainer of boxer "Irish" Micky Ward, played by Mark Wahlberg. Bale again showed his ability to reshape his body with another gaunt, skeletal transformation.

Bale then turned to another auteur, Yimou Zhang, for the epic The Flowers of War (2011), in which Bale portrayed a priest trapped in the midst of the Rape of Nanking. Bale earned headlines for his attempt to visit with Chinese civil-rights activist Chen Guangcheng, which was blocked by the Chinese government.

Bale capped his role as Bruce Wayne/Batman in The Dark Knight Rises (2012); in the wake of the Aurora, Colorado tragedy, Bale made a quiet pilgrimage to the state to visit with survivors of the attack that left theatergoers dead and injured. He also starred in the thriller Out of the Furnace (2013) with Crazy Heart (2009) writer/director Scott Cooper, and the drama-comedy American Hustle (2013), reuniting with David O. Russell.

Bale will re-team with The New World (2005) director Terrence Malick for two upcoming projects: Knight of Cups (2015) and an as-yet-untitled drama.

In his personal life, he devotes time to charities including Greenpeace and the World Wildlife Foundation. He lives with his wife, Sibi Blazic, and their two children.

Kevin Conroy was born on November 30, 1955 in Westbury, New York. At age 17, Kevin earned a full scholarship to attend Juilliard's drama division, where he studied under actor John Houseman. In 1978, after graduating from Juilliard, he toured with "The Acting Company", Houseman's acting group, and in 1979, he went on the national tour of "Deathtrap". In 1980, he was cast in the daytime soap opera Another World (1964). However, he soon missed the theatre, and so he became associated with the Old Globe Theatre in San Diego, California, where he performed in "Hamlet" and "A Midsummer Night's Dream". From 1980 to 1985, he acted in a variety of contemporary and classic theatre pieces, including the Broadway production of "Eastern Standard" and "Lolita". He is very respected in theatre circles for his interpretation of Shakespearean characters, and in 1984, he played the title role in "Hamlet" in the New York Shakespeare Festival. Kevin returned to television in the television movie Covenant (1985). He was a series regular on Ohara (1987) in 1987, and on Tour of Duty (1987) from 1987 to 1988, before starring in a series of television movies. He is best known for providing the title role in the animated Batman: The Animated Series (1992) series.

Benjamin Géza "Ben" Affleck-Boldt was born on August 15, 1972 in Berkeley, California and raised in Cambridge, Massachusetts, to mother Chris Anne (Boldt), a school teacher, and father Timothy Byers "Tim" Affleck, a social worker. Ben has a younger brother, actor Casey Affleck, who was born in 1975. He is of mostly English, Irish, German, and Scottish ancestry. His middle name, Géza, is after a Hungarian family friend who was a Holocaust survivor.

Affleck wanted to be an actor ever since he could remember, and his first acting experience was for a Burger King commercial, when he was on the PBS mini-series, The Voyage of the Mimi (1984). It was also at that age when Ben met his lifelong friend and fellow actor, Matt Damon. They played little league together and took drama classes together. Ben's teen years consisted of mainly TV movies and small television appearances including Hands of a Stranger (1987) and The Second Voyage of the Mimi (1988). He made his big introduction into feature films in 1993 when he was cast in Dazed and Confused (1993). After that, he did mostly independent films like Kevin Smith's Mallrats (1995) and Chasing Amy (1997) which were great for Ben's career, receiving renowned appreciation for his works at the Sundance film festival. But the success he was having in independent films didn't last much longer and things got a little shaky for Ben. He was living in an apartment with his brother Casey and friend Matt, getting tired of being turned down for the big roles in films and being given the forgettable supporting ones. Since Matt was having the same trouble, they decided to write their own script, where they could call all the shots. So, after finishing the script for Good Will Hunting (1997), they gave it to their agent, Patrick Whitesell, who showed it to a few Hollywood studios, finally being accepted by Castle Rock. It was great news for the two, but Castle Rock wasn't willing to give Ben and Matt the control over the project they were hoping for. It was friend Kevin Smith who took it to the head of Miramax who bought the script giving Ben and Matt the control they wanted and, in December 5, 1997, Good Will Hunting (1997) was released, making the two unknown actors famous. The film was nominated for 9 Academy Awards and won two, including Best Original Screenplay for Ben and Matt. The film marked Ben's breakthrough role, in which he was given for the first time the chance to choose roles instead of having to go through grueling auditions constantly.

Affleck chose such roles in the blockbusters Armageddon (1998), Shakespeare in Love (1998), and Pearl Harbor (2001). In the early years of the 2000s, he also starred in the box office hits Changing Lanes (2002), The Sum of All Fears (2002), and Daredevil (2003), as well as the disappointing comedies Gigli (2003) and Surviving Christmas (2004). While the mid 2000s were considered a career downturn for Affleck, he received a Golden Globe nomination for his performance in Hollywoodland (2006). In the several years following, he played supporting roles, including in the films Smokin' Aces (2006), He's Just Not That Into You (2009), State of Play (2009), and Extract (2009). He ventured into directing in 2007, with the thriller Gone Baby Gone (2007), which starred his brother, Casey Affleck, and was well received. He then directed, co-wrote, and starred in The Town (2010), which was named to the National Board of Review Top Ten Films of the year. For the political thriller Argo (2012), which he directed and starred in, Affleck won the Golden Globe Award and BAFTA Award for Best Director, and the Academy Award, Golden Globe Award, and BAFTA Award for Best Picture (Affleck's second Oscar win).

In 2014, Affleck headlined the book adaptation thriller Gone Girl (2014). He starred as Bruce Wayne/Batman in the superhero film Batman v Superman: Dawn of Justice (2016), Suicide Squad (2016), and Justice League (2017). He reprised the role in Zack Snyder's Justice League (2021) and he will next appear as Batman in Aquaman and the Lost Kingdom (2023) and The Flash (2023).

Recently he has given praise-worthy performances in The Way Back (2020) as a recovering alcoholic, The Last Duel (2021) (notably he also co-wrote the script), and a scene-stealing golden globe nominated performance in The Tender Bar (2021).

Quirky, inventive and handsome American actor Michael Keaton first achieved major fame with his door-busting performance as fast-talking ideas man Bill Blazejowski, alongside a nerdish morgue attendant (Henry Winkler), in Night Shift (1982). He played further comedic roles in Mr. Mom (1983), Johnny Dangerously (1984), and Beetlejuice (1988), earned further acclaim for his dramatic portrayal of Bruce Wayne / Batman in Tim Burton's Batman (1989) and Batman Returns (1992), and since then, has moved easily between film genres, ranging from drama and romantic comedy to thriller and action.

Keaton was born Michael John Douglas on September 5, 1951 in Coraopolis, Pennsylvania, to Leona Elizabeth (Loftus), a homemaker, and George A. Douglas, a civil engineer and surveyor. He is of Irish, as well as English, Scottish, and German, descent. Michael studied speech for two years at Kent State, before dropping out and moving to Pittsburgh. An unsuccessful attempt at stand-up comedy led Keaton to working as a TV cameraman in a cable station, and he came to realize he wanted to work in front of the cameras. Keaton first appeared on TV in several episodes of Mister Rogers' Neighborhood (1968).

He left Pittsburgh and moved to Los Angeles to begin auditioning for TV. He began cropping up in popular TV shows including Maude (1972) and The Mary Tyler Moore Hour (1979). Around this time, Keaton decided to use an alternative surname to remove confusion with better-known actor Michael Douglas. He looked into the "K"'s for surnames and thought it was inoffensive to chose 'Keaton'. His next break was scoring a co-starring role alongside Jim Belushi in the short-lived comedy series Working Stiffs (1979), which showcased his comedic talent and led to his co-starring role in Night Shift (1982). Keaton next scored the lead in the comedy hits Mr. Mom (1983), Johnny Dangerously (1984) , Gung Ho (1986), the Tim Burton horror-comedy Beetlejuice (1988), and The Dream Team (1989).

Keaton's career was given another major boost when he was again cast by Tim Burton, this time as the title comic book superhero, millionaire playboy/crime-fighter Bruce Wayne, in Batman (1989). Burton cast him because he thought that Keaton was the only actor who could portray someone who has the kind of darkly obsessive personality that the character demands. To say there were howls of protest by fans of the caped crusader comic strip is an understatement! Warner Bros. was deluged with thousands of letters of complaint commenting that comedian Keaton was the wrong choice for the Caped Crusader, given his prior work and the fact that he lacked the suave, handsome features and tall, muscular physicality often attributed to the character in the comic books. However, their fears were proven wrong when Keaton turned in a sensational performance, and he held his own on screen with opponent Jack Nicholson, playing the lunatic villain, "The Joker". Keaton's dramatic work earned widespread acclaim from critics and audiences alike, and Batman (1989) became one of the most successful films of the year.

Keaton remained active during the 1990s, appearing in a wide range of films. Keen to diversify his work, Keaton starred as a psychotic tenant in Pacific Heights (1990), as a hard-working cop in One Good Cop (1991), and then donned the black cape and cowl once more for Batman Returns (1992). He remained in demand during the 1990s, appearing in a wide range of films, including the star-studded Shakespearian Much Ado About Nothing (1993), the drama My Life (1993), another Ron Howard comedy The Paper (1994), with sexy Andie MacDowell in Multiplicity (1996), twice in the same role, dogged Elmore Leonard character Agent Ray Nicolette, in Jackie Brown (1997) and Out of Sight (1998). He also played a killer in the mediocre thriller Desperate Measures (1998).

In the 2000s, Keaton appeared in several productions with mixed success, including Live from Baghdad (2002), First Daughter (2004), and Herbie: Fully Loaded (2005). He also provided voices for characters in the animated films Cars (2006), Toy Story 3 (2010), and Minions (2015).

He returned to major film roles in the 2010s, co-starring in The Other Guys (2010), RoboCop (2014) and Need for Speed (2014). Also that year, Keaton starred alongside Zach Galifianakis, Edward Norton, Emma Stone, and Naomi Watts in Birdman or (The Unexpected Virtue of Ignorance) (2014), a film by 21 Grams (2003) and Biutiful (2010) director Alejandro G. Iñárritu. In the film, Keaton plays Riggan Thomson, a screen actor, famous for playing the iconic titular superhero, who puts on a Broadway play based on a Raymond Carver short story, to regain his former glory. Keaton's critically praised lead performance earned him a Golden Globe Award for Best Actor in a Musical or Comedy, the Critics' Choice Award for Best Actor and Best Actor in a Comedy, and nominations for the Screen Actors Guild Award, British Academy Film Award, and Academy Award for Best Actor.

In 2015, he played a journalist in Spotlight (2015), which, like Birdman, won the Academy Award for Best Picture. In 2016, he starred as Ray Kroc, the developer of McDonald's, in the drama The Founder (2016).

He is a visiting scholar at Carnegie Mellon University.

Voice actor and former stand-up comic Roger Craig Smith is a man of a thousand voices. In just one animation production alone, Roger voiced more than 170 characters for the Emmy award-winning Cartoon Network series Regular Show. He's the titular character "Mouse", as well as "Moose" for Amazon Prime's Emmy-nominated children's series If You Give a Mouse a Cookie. For Netflix, Roger voices "Brock", "Mayor Fowler", "Cousin Ashley" and many more on Dreamworks' hit series from Tony Hale, Archibald's Next Big Thing. Also on Netflix, Roger voices "Pinkeye", "Bobby", and "Billy" in Dreamworks Animation's Harvey Girls Forever. On Cartoon Network, he voices "Sonic the Hedgehog" in Sonic Boom, "Hawkodile" and "Richard" for WB/LEGO's Unikitty!, "Diamondhead", "Forever Knight" and "Steam Smythe" on Ben-10, "Percy" and "Belson" in Clarence, "Bob" and "Schedulebot" in Powerpuff Girls. On Disney XD's NAACP Image Award-nominated Avengers: Black Panther's Quest, Roger has been voicing legendary superhero "Captain America" since 2012. He voices "Batman" in in the DC/WB film Superman: Red Son, as well as in the trilogy Batman Unlimited. His impact in the genre of anime includes voicing "Batman" in WB's feature film Batman Ninja, the maniacal "Deidara" in Naruto and "Shinji Hirako" in Bleach. Roger voiced "Sonic the Hedgehog" in Disney's blockbuster features Wreck-It Ralph and Wreck-It Ralph 2: Ralph Breaks the Internet and was called on by Disney in 2013 to voice lead villain "Ripslinger" in Disney's hit feature Planes.

Roger's legacy as an actor in video games is extensive. Voice of gaming icon "Ezio Auditore da Firenze" from Ubisoft's Assassin's Creed, with more than 28 million copies sold worldwide. He's the voice of the charming Legend "Mirage" in Respawn's record-setting Apex Legends, with over 70 million players in 2019 alone. WB chose Roger to voice the legendary "Batman" in WB's Batman: Arkham Origins and Arkham Origins: Blackgate. Roger has been voicing "Sonic the Hedgehog" for SEGA since 2010 and earned early gaming fandom when he voiced "Chris Redfield" in the Resident Evil series of games.

Roger is the announcer/narrator for NBC's smash hit World of Dance, averaging millions of viewers each episode. He's narrated more than 1,000 episodes of other shows, including TLC's longest-running prime-time series Say Yes to the Dress and DIY Network's Crashers series. He's voiced multiple promo campaigns for major networks and is the imaging/promo voice for the world-famous KROQ 106.7FM in Los Angeles. Multiple national retail campaigns continue to utilize Roger to enhance their message to consumers across all mediums.

An average day begins with sessions from his home studio at 7am for national retail clients, heading into LA from 9am-6pm for animation/game sessions, then back to his home studio for more promo/narration sessions in the evening.

Raised in SoCal and voted "Class Clown" in 8th grade, he focused his creativity toward training in musical theater. He spoke at both his 8th and 12th grade graduations, was elected freshman class president in high school, and hosted a live local TV talk show while earning his B.A. in Screenwriting from Chapman University...all while pursuing a career in stand-up comedy. After working as a comic for 5 years, he left stand-up to pursue voice acting full-time in 2005.

Knowing he's got fans of all ages on social media, Roger keeps his posts apolitical and family-friendly. An avid supporter of CHOC (Chidlren's Hospital Orange County), he frequently visits the hospital to meet with patients. He's currently learning ASL (American Sign Language) and enjoys getting outdoors as often as possible to pursue his passion for nature, hiking/mountain biking, and nightscape/astrophotography, which he shares regularly with his followers on Instagram and Twitter. (@rogercraigsmith).

Adam West was born William West Anderson on September 19, 1928 in Walla Walla, Washington, to parents Otto West Anderson, a farmer, and his wife Audrey V. (Speer), an opera singer. At age 10, in 1938, West had a cache of comic books; and starting in 1939, Batman, who appeared in Detective Comics, made a big impression on him--the comic hero was part bat-man (a la Count Dracula) and part world's greatest detective (a la Charlie Chan and Sherlock Holmes). When his mother remarried to a Dr. Paul Flothow, she took West and his younger brother, John, to Seattle. At age 14, West attended Lakeside School, then went to Whitman College, where he got a degree in literature and psychology. During his last year of college, he married 17-year-old Billie Lou Yeager.

West got a job as a disc jockey at a local radio station, then enrolled at Stanford for post-grad courses. Drafted into the army, he spent the next two years starting military television stations, first at San Luis Obispo, California, then at Fort Monmouth, New Jersey. Afterwards, West and his wife toured Europe, visiting Germany, Switzerland and Italy's Isle of Capri. When the money ran out, he joined a childhood and college buddy, Carl Hebenstreit, who was starring in the kiddie program "The Kini Popo Show" in Hawaii. West would eventually replace Carl but not the other star, Peaches the Chimp. In 1956, he got a divorce and married a beautiful girl, originally from Tahiti, named Ngatokoruaimatauaia Frisbie Dawson (he called her "Nga" for short). They had a daughter, Jonelle (born 1957), and a son, Hunter (born 1958). In 1959, West came to Hollywood. He adopted the stage name "Adam West", which fit his roles, as he was in some westerns.

After seven years in Tinseltown, he achieved fame in his signature role as Bruce Wayne / Batman, on the wildly popular ABC-TV series Batman (1966) (though he has over 60 movie and over 80 television guest appearance credits, "Batman" is what the fans remember him for). The series, which lasted three seasons, made him not just nationally but internationally famous. The movie version, Batman: The Movie (1966), earned West the "Most Promising New Star" award in 1967. The downside was that the "Batman" fame was partly responsible for ruining his marriage, and he was typecast and almost unemployable for a while after the series ended (he did nothing but personal appearances for two years).

In 1970, he met and then married Marcelle Tagand Lear, and picked up two stepchildren, Moya and Jill. In addition, they had two children of their own: Nina West in 1976 and Perrin in 1979. You can't keep a good actor down--West's career took off again, and he appeared in 50 projects after that: movies, television movies and sometimes doing voices on television series. West wrote his autobiography, "Back to the Batcave" (1994). One of his most prized possessions was a drawing of Batman by Bob Kane with the inscription "To my buddy, Adam, who breathed life into my pen and ink creation". Beginning in 2000, West made guest appearances on the animated series Family Guy (1999), on which he played Mayor Adam West, the lunatic mayor of Quahog, Rhode Island.

On June 9, 2017, Adam West died at age 88 after a brief battle with leukemia in Los Angeles, California. On June 15, 2017, Los Angeles shone the bat-signal on City Hall, and Walla Walla shone the bat-signal on the Whitman Tower, both as a tribute to West.

Val Kilmer was born in Los Angeles, California, to Gladys Swanette (Ekstadt) and Eugene Dorris Kilmer, who was a real estate developer and aerospace equipment distributor. His mother, born in Indiana, was from a Swedish family, and his father was from Texas. Val studied at Hollywood's Professional's School and, in his teens, entered Juilliard's drama program. His professional acting career began on stage, and he still participates in theater; he played Hamlet at the 1988 Colorado Shakespeare Festival. His film debut was in the 1984 spoof Top Secret! (1984), wherein he starred as blond rock idol Nick Rivers. He was in a number of films throughout the 1980s, including the 1986 smash Top Gun (1986). Despite his obvious talent and range, it wasn't until his astonishingly believable performance as Jim Morrison in Oliver Stone's The Doors (1991) that the world sat up and took notice. Kilmer again put his good baritone to use in the movie, performing all of the concert pieces. Since then, he has played two more American legends, Elvis Presley in True Romance (1993) and Doc Holliday in Tombstone (1993). In July 1994, it was announced that Kilmer would be taking over the role of Batman/Bruce Wayne from Michael Keaton.

George Timothy Clooney was born on May 6, 1961, in Lexington, Kentucky, to Nina Bruce (née Warren), a former beauty pageant queen, and Nick Clooney, a former anchorman and television host (who was also the brother of singer Rosemary Clooney). He has Irish, English, and German ancestry. Clooney spent most of his youth in Ohio and Kentucky, and graduated from Augusta High School. He was very active in sports such as basketball and baseball, and tried out for the Cincinnati Reds, but was not offered a contract.

After his cousin, Miguel Ferrer, got him a small role in a feature film, Clooney began to pursue acting. His first major role was on the sitcom E/R (1984) as Ace. More roles soon followed, including George Burnett, the handsome handyman on The Facts of Life (1979); Booker Brooks, a supervisor on Roseanne (1988); and Detective James Falconer on Sisters (1991). Clooney had his breakthrough when he was cast as Dr. Doug Ross on the award-winning drama series ER (1994), opposite Anthony Edwards, Noah Wyle and Julianna Margulies.

While filming "ER" (1994), Clooney starred in a number of high profile film roles, such as Robert Rodriguez's From Dusk Till Dawn (1996), and One Fine Day (1996), opposite Michelle Pfeiffer. In 1997, Clooney took on the role of Batman in Joel Schumacher's Batman & Robin (1997). The film was a moderate success in the box office, but was slammed by critics, notably for the nipple-laden Batsuit. Clooney went on to star in Steven Soderbergh's Out of Sight (1998), Terrence Malick's The Thin Red Line (1998), and David O. Russell's Three Kings (1999).

In 1999, Clooney left "ER" (1994) (though he would return for the season finale) and appeared in a number of films, including O Brother, Where Art Thou? (2000), The Perfect Storm (2000) and Ocean's Eleven (2001). Collaborating once again with Steven Soderbergh, Ocean's Eleven (2001) received critical acclaim, earned more than $450 million at the box office, and spawned two sequels: Ocean's Twelve (2004) and Ocean's Thirteen (2007).

In 2002, Clooney made his directorial debut with Confessions of a Dangerous Mind (2002), an adaptation of TV producer Chuck Barris' autobiography. This was the first film under the banner of Section Eight Productions, a production company he founded with Steven Soderbergh. The company also produced many acclaimed films, including Far from Heaven (2002), Syriana (2005), A Scanner Darkly (2006) and Good Night, and Good Luck. (2005). Clooney won his first Oscar for Best Supporting Actor in Syriana (2005), and was nominated for Best Director and Best Original Screenplay for Good Night, and Good Luck. (2005).

In 2006, Section Eight Productions was shut down so that Soderbergh could concentrate on directing, and Clooney founded a new production company, Smokehouse Productions, with his friend and longtime business partner, Grant Heslov.

Clooney went on to produce and star in Michael Clayton (2007) (which earned him an Oscar nomination for Best Actor), directed and starred in Leatherheads (2008), and took leading roles in Burn After Reading (2008), The Men Who Stare at Goats (2009), Fantastic Mr. Fox (2009), and Jason Reitman's Up in the Air (2009). Clooney received critical acclaim for his performance in Up in the Air (2009) and was nominated for several awards, including a Golden Globe Award and Academy Award. He didn't win that year, but took home both Best Actor awards (as well as countless nominations) for his role as a father who finds out his wife was unfaithful as she lays in a coma in Alexander Payne's The Descendants (2011). Through his career, Clooney has been heralded for his political activism and humanitarian work. He has served as one of the United Nations Messengers of Peace since 2008, has been an advocate for the Darfur conflict, and organized the Hope for Haiti telethon, to raise money for the victims of the 2010 earthquake. In March 2012, Clooney was arrested for civil disobedience while protesting at the Sudanese embassy in Washington, D.C.

Clooney was married to actress Talia Balsam, from 1989 until 1993. After their divorce, he swore he would never marry again. Michelle Pfeiffer and Nicole Kidman bet him $10,000 that he would have children by the age of 40, and sent him a check shortly after his birthday. Clooney returned the funds and bet double or nothing he wouldn't have children by the age of 50. Although he has remained a consummate bachelor, Clooney has had many highly publicized relationships, including with former WWE wrestler Stacy Keibler. In 2014, he married lawyer and activist Amal Clooney, with whom he has two children, twins.