Centuries following nuclear war, a teen leaves the safety of an underground vault in order to find their father, who left in hopes of creating a water purifier.
When the nations of the world rely upon private military companies to fight their battles for them, renegade Liquid Ocelot emerges as the head of a potent coalition of mercenary powers. Solid Snake returns to save the world once again.
A popular politician is murdered and Faith's sister is arrested, whilst Faith escapes. Now she must try to unravel the circumstances of Pope's murder and to relieve her sister.