Kat Graham and Steven R. McQueen in The Vampire Diaries (2009)

Paul Wesley and Nina Dobrev in The Vampire Diaries (2009)

Jeff Daniels and Emily Mortimer in The Newsroom (2012)

Patrick Dempsey, Ellen Pompeo, and Jela K. Moore in Grey's Anatomy (2005)

Mischa Barton and Ben McKenzie in The O.C. (2003)

Jesse Tyler Ferguson and Eric Stonestreet in Modern Family (2009)

Jessica Capshaw and Sara Ramirez in Grey's Anatomy (2005)

David Boreanaz and Charisma Carpenter in Angel (1999)

Jennifer Aniston and David Schwimmer at an event for Scream 2 (1997)

AnnaLynne McCord and Matt Lanter in 90210 (2008)

Darren Criss and Chris Colfer in Glee (2009)

Anna Friel and Lee Pace in Pushing Daisies (2007)

Lea Michele and Cory Monteith in Glee (2009)

Daniel Dae Kim and Yunjin Kim in Lost (2004)

Sarah Michelle Gellar and David Boreanaz in Angel (1999)

Josh Holloway and Elizabeth Mitchell in Lost (2004)

Kevin McKidd and Sandra Oh in Grey's Anatomy (2005)

Sarah Jessica Parker and Chris Noth in Sex and the City (1998)

Leighton Meester and Ed Westwick in Gossip Girl (2007)

James Lafferty and Bethany Joy Lenz in One Tree Hill (2003)

Kevin McHale and Jenna Ushkowitz in Glee (2009)

Penn Badgley and Blake Lively in Gossip Girl (2007)

Wentworth Miller and Sarah Wayne Callies in Prison Break (2005)

Julie Bowen and Ty Burrell in Modern Family (2009)

Justin Bartha and Andrew Rannells in The New Normal (2012)

Joseph Morgan and Candice King in The Vampire Diaries (2009)

Todd Lowe and Carrie Preston in True Blood (2008)

Michael C. Hall and Mathew St. Patrick in Six Feet Under (2001)