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Robert Pershing Wadlow was born on February 22, 1918 in Alton, Illinois. His height of 8' 11.1" qualifies him as the tallest person in history, as recorded in the Guinness Book of Records. Robert was the first born of Addie and Harold Wadlow. He had two sisters, Helen and Betty, and two brothers, Eugene and Harold Jr., all of whom were of average height and weight. His excessive height was due to an overactive pituitary gland, for which there was no treatment at the time. According to records kept in his hometown of Alton, Robert enjoyed collecting stamps, photography, and the Boy Scouts, becoming the world's tallest Boy Scout when he was 13 years old. He was also regarded as being very quiet, earning him the nickname "Gentle Giant." When he turned 20 Robert traveled for the International Shoe Company, who provided him with free shoes (which usually cost $100 a pair). His father had to remove the front passenger seat of the family car so Robert could sit in the back seat. Due to poor circulation, Robert had little sensation in his feet and did not notice when problems like blisters developed. In July of 1940 a blister on his ankle led to an infection that, despite treatment, ended his life on the morning of July 15th. Robert was buried in his hometown of Alton. All city businesses closed for the funeral, which was attended by tens of thousands of people. The 1,000-pound casket required 12 pallbearers. In 1985 a life-sized bronze statue of Robert was erected on the campus of the Southern Illinois University School of Dental Medicine.

Originally a student of pre-law at Widener University, and later majoring in Criminal Justice at West Chester University, Matthew started his career by making appearances on The Howard Stern Show (1990), The Oprah Winfrey Show (1986), and music videos of Iron Maiden, Marilyn Manson, and Blondie. Matthew would later amass a cult following for memorable roles such as "Tiny" in Rob Zombie's House of 1000 Corpses (2003), and Karl the giant in Tim Burton's Big Fish (2003). In the midst of working on a biopic about André René Roussimoff, Matthew died on August 9, 2005 from natural causes. The Devil's Rejects (2005) (House of 1000 Corpses (2003)'s sequel) was dedicated to him.

André René Roussimoff was born in a small farming community in Grenoble, France to Boris and Marian Rouismoff. His parents and four siblings were all of normal size, but André suffered from acromegaly, a hormonal disorder that results when the pituitary gland produces excess growth hormone. As the Giant grew up (very quickly, as he reached the height of 6' 3" by the age of 12) he began to often disagree with his parents. He left home at 14 and obtained a job with a furniture-moving firm and began to play rugby. At 17 he was seen training at a gym by several professional wrestlers. Impressed by his size, they taught him some basic wrestling skills and built a friendship with him. Later, when one of the wrestlers was injured, André stepped in for him. He would wrestle for nearly thirty more years. By his early 20s André had wrestled in Algeria, South Africa, Morocco, Tunisia, England, Scotland, and most of non-Communist Europe but had not found fame. In 1971 he came to North America under the name Jean Ferre and was mildly popular in Canada. Then he met a New York based booker by the name of Vincent J. McMahon (often incorrectly referred to as "Vince McMahon Sr") who renamed him "Andre the Giant," and billed him as 7' 4" (Andre was really closer to 7'). Soon Andre the Giant became a national sensation and was a much sought after wrestler. In addition he participated in television, movies, and commercials. With his wealth the Giant bought a ranch in Ellerbe, North Carolina where he would live during his rare time off and after he retired from wrestling in 1990. He died while in France after attending his father's funeral. André was cremated and his ashes were spread across his ranch. He is survived by his one daughter.

Shaquille O'Neal is a retired professional American basketball player who is a sports analyst on the television program Inside the NBA on TNT. He is considered one of the greatest players in National Basketball Association (NBA) history. He was one of the tallest and heaviest players ever. O'Neal played for six teams over his 19-year career.

O'Neal's individual accolades include the 1999-2000 MVP award, the 1992-93 NBA Rookie of the Year award, 15 All-Star game selections, three All-Star Game MVP awards, three Finals MVP awards, two scoring titles, 14 All-NBA team selections, and three NBA All-Defensive Team selections. He is one of only three players to win NBA MVP, All-Star game MVP and Finals MVP awards in the same year (2000); the other players are Willis Reed in 1970 and Michael Jordan in 1996 and 1998. Largely due to his ability to dunk the basketball, O'Neal ranks third all-time in field goal percentage (58.2%). O'Neal was elected into the Naismith Memorial Basketball Hall of Fame in 2016. He was elected to the FIBA Hall of Fame in 2017.

In addition to his basketball career, O'Neal has released four rap albums, with his first, Shaq Diesel, going platinum. O'Neal is an electronic music producer, and touring DJ, known as Diesel. He has appeared in numerous films and has starred in his own reality shows.

Gheorghe, a native of the Transylvania region of Romania, has become one of the top centers in the NBA. A dominant force in Europe, he began his NBA career feeling a little out of place. That quickly changed when he bumped the Bullets regular center and became the starter. He contributed almost immediately with his large powerful arms and towering presence. Gheorghe's height is not due to genetics, but to a pitituary gland condition. His late mother was 5'7" and his father is 5'9". Gheorghe, once regarded as an oddity by many, went on to win the 1995-1996 NBA Most Improved Player award. He has led the NBA in field-goal percentage in both the 95-96 season and the 96-97 season. His presence is sorely missed by the Wizards during the 97-98 season, as he has not played a single minute due to injury. When he returns however, his fans and teammates will certainly be relieved to know that "Big Gheorghe" is back patrolling the paint.

Yao Ming was born on 12 September 1980 in Shanghai, China. He is an actor, known for Seola's Journal, Amazing (2013) and Yao Ming and Children Affected b HIV/AIDS (2005). He has been married to Ye Li since 6 August 2007. They have one child.

Manute Bol was born on 16 October 1962 in Gogrial, Sudan. He was an actor, known for NBA Hardwood Classics (1990), Famous: The Tom Gross Story and Hardcore TV (1992). He was married to Ajok Giugwol. He died on 19 June 2010 in Charlottesville, Virginia, USA.

Shawn Bradley is known for Game Changers (2011).