A half-shark and half-octopus creature created for the military creates a whole lot of terror in Mexico, while the scientist who helped to create it tries to either capture or kill it.
When a mad scientist hybridizes the genes of a killer whale and a wolf, this creates the whalewolf and, once again, it is up to the sharktopus to stop it.
An American scientist creates a half-pterosaur and half-barracuda creature named the pteracuda which inevitably escapes, leaving it up to the sharktopus to stop it.