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- CreatorDavid CraneMarta KauffmanStarsJennifer AnistonCourteney CoxLisa KudrowFollows the personal and professional lives of six twenty to thirty year-old friends living in the Manhattan borough of New York City.
- CreatorDavid BenioffD.B. WeissStarsEmilia ClarkePeter DinklageKit HaringtonNine noble families fight for control over the lands of Westeros, while an ancient enemy returns after being dormant for millennia.
- CreatorLarry DavidJerry SeinfeldStarsJerry SeinfeldJulia Louis-DreyfusMichael RichardsThe continuing misadventures of neurotic New York City stand-up comedian Jerry Seinfeld and his equally neurotic New York City friends.
- CreatorJames Manos Jr.StarsMichael C. HallJennifer CarpenterDavid ZayasHe's smart. He's lovable. He's Dexter Morgan, America's favorite serial killer, who spends his days solving crimes and nights committing them.
- CreatorChris CarterStarsDavid DuchovnyGillian AndersonMitch PileggiTwo F.B.I. Agents, Fox Mulder the believer and Dana Scully the skeptic, investigate the strange and unexplained, while hidden forces work to impede their efforts.
- CreatorDarren StarStarsHeather LocklearAndrew ShueCourtney Thorne-SmithClassic serial drama around a group of friends living in Melrose Place, California.
- CreatorDarren StarStarsJason PriestleyShannen DohertyLuke PerryA group of friends living in Beverly Hills, California make their way through life from their school days into adulthood.
- CreatorMarshall HerskovitzEdward ZwickStarsSela WardBilly CampbellJeffrey NordlingA divorced father and a soon-to-be divorced mother meet and begin a romantic courtship which is always complicated by their respective children and their own life problems.
- CreatorBrenda HamptonStarsStephen CollinsCatherine HicksJessica BielEric Camden, a minister, and his wife Annie deal with the drama of having seven children, ranging from toddlers to adults with families of their own.
- CreatorStephanie SavageJosh SchwartzStarsBlake LivelyLeighton MeesterPenn BadgleyPrivileged teens living on the Upper East Side of New York can hide no secret from the ruthless blogger who is always watching.
- CreatorAmy Sherman-PalladinoStarsLauren GrahamAlexis BledelKeiko AgenaA dramedy centering around the relationship between a thirtysomething single mother and her teen daughter living in Stars Hollow, Connecticut.
- CreatorJosh SchwartzStarsMischa BartonAdam BrodyPeter GallagherA troubled youth becomes embroiled in the lives of a close-knit group of people in the wealthy, upper-class neighborhood of Newport Beach, Orange County, California.
- CreatorShonda RhimesStarsKate WalshPaul AdelsteinKaDee StricklandA spin-off of the medical drama "Grey's Anatomy" centering on the life of neonatal surgeon Addison Montgomery.
- CreatorJ.J. AbramsJeffrey LieberDamon LindelofStarsJorge GarciaJosh HollowayYunjin KimThe survivors of a plane crash are forced to work together in order to survive on a seemingly deserted tropical island.
- CreatorShonda RhimesMichelle LirtzmanStarsEllen PompeoChandra WilsonJames Pickens Jr.A drama centered on the personal and professional lives of five surgical interns and their supervisors.
- CreatorMichael CrichtonStarsAnthony EdwardsGeorge ClooneyJulianna MarguliesThe doctors who work in the ER at the County General Hospital in Chicago grapple with ups and downs in their personal and professional lives while trying to give apt medical care to their patients.
- StarsKate WinsletGuy PearceEvan Rachel WoodDivorced single mom Mildred Pierce decides to open a restaurant business, which tears at the already-strained relationship with her ambitious elder daughter, Veda.
- CreatorKevin WilliamsonStarsJames Van Der BeekKatie HolmesMichelle WilliamsTwo childhood best friends, Dawson and Joey, go through different stages of adolescence together. Their friendship is later tested when they both start a relationship with different people.
- CreatorChristopher KeyserAmy LippmanStarsMatthew FoxScott WolfNeve CampbellFive siblings raise each other following their parents' untimely deaths.
- CreatorDavid ShoreStarsHugh LaurieOmar EppsRobert Sean LeonardUsing a crack team of doctors and his wits, an antisocial maverick doctor specializing in diagnostic medicine does whatever it takes to solve puzzling cases that come his way.
- CreatorJ.J. AbramsMatt ReevesStarsKeri RussellScott SpeedmanScott FoleyA young girl, fresh out of high school, follows her high school crush to college to be near him.
- CreatorGreg BerlantiStarsTreat WilliamsGregory SmithEmily VanCampA widowed brain surgeon from Manhattan moves his two children to the small mountain town of Everwood, Colorado.
- CreatorRyan MurphyStarsDylan WalshJulian McMahonJoely RichardsonTwo plastic surgeons--one a dedicated family man and one an unscrupulous playboy--strive to maintain their business whilst having to work their way through numerous hardships ranging from personal to clients with criminal connections.
- CreatorAaron SorkinStarsMartin SheenRob LoweAllison JanneyInside the lives of staffers in the West Wing of the White House.
- CreatorKari LizerStarsJulia Louis-DreyfusClark GreggHamish LinklaterA divorced mom tries to keep pace with everyone around her.