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- CreatorDavid ShoreStarsHugh LaurieOmar EppsRobert Sean LeonardUsing a crack team of doctors and his wits, an antisocial maverick doctor specializing in diagnostic medicine does whatever it takes to solve puzzling cases that come his way.
- CreatorTim KringStarsJill HennessyMiguel FerrerRavi KapoorBrash, stubborn and resourceful ME Jordan Cavanaugh revives her career in Boston, occasionally breaking the rules and ticking off the cops or her co-workers. On the home front, she gets crime-solving help from her retired-cop dad.
- CreatorAndy BreckmanStarsTony ShalhoubJason Gray-StanfordTed LevineThe series follows Adrian Monk, a brilliant former San Francisco detective, who now consults the police as a private consultant whilst battling with an obsessive-compulsive disorder.
- CreatorJ.J. AbramsJeffrey LieberDamon LindelofStarsJorge GarciaJosh HollowayYunjin KimThe survivors of a plane crash are forced to work together in order to survive on a seemingly deserted tropical island.
- CreatorDavid E. KelleyStarsJames SpaderWilliam ShatnerCandice BergenBoston Legal is a spin-off of the long-running David E. Kelley series The Practice (1997), following the exploits of former Practice character Alan Shore (James Spader) at the legal firm of Crane, Poole, and Schmidt.
- CreatorJames DuffStarsKyra SedgwickJ.K. SimmonsCorey ReynoldsDeputy Police Chief Brenda Johnson runs the Priority Homicide Division of the LAPD with an unorthodox style. Her innate ability to read people and obtain confessions helps her and her team solve the city's toughest, most sensitive cases.
- CreatorMark FrostDavid LynchStarsKyle MacLachlanMichael OntkeanMädchen AmickAn idiosyncratic FBI agent investigates the murder of a young woman in the even more idiosyncratic town of Twin Peaks.
- CreatorMichael CrichtonStarsAnthony EdwardsGeorge ClooneyJulianna MarguliesThe doctors who work in the ER at the County General Hospital in Chicago grapple with ups and downs in their personal and professional lives while trying to give apt medical care to their patients.
- CreatorGene RoddenberryStarsPatrick StewartBrent SpinerJonathan FrakesSet almost 100 years after Captain Kirk's 5-year mission, a new generation of Starfleet officers sets off in the U.S.S. Enterprise-D on its own mission to go where no one has gone before.
- CreatorRick BermanMichael PillerJeri TaylorStarsKate MulgrewRobert BeltranRoxann DawsonPulled to the far side of the galaxy, where the Federation is seventy-five years away at maximum warp speed, a Starfleet ship must cooperate with Maquis rebels to find a way home.
- CreatorRick BermanMichael PillerStarsAvery BrooksRene AuberjonoisCirroc LoftonIn the vicinity of the liberated planet of Bajor, the Federation space station Deep Space Nine guards the opening of a stable wormhole to the far side of the galaxy.
- CreatorRick BermanBrannon BragaStarsScott BakulaJohn BillingsleyJolene BlalockA century before Captain Kirk's five-year mission, Jonathan Archer captains the United Earth ship Enterprise during the early years of Starfleet, leading up to the Earth-Romulan War and the formation of the Federation.
- CreatorGlen A. LarsonRonald D. MooreStarsEdward James OlmosMary McDonnellJamie BamberWhen an old enemy, the Cylons, resurface and obliterate the 12 colonies, the crew of the aged Galactica protect a small civilian fleet - the last of humanity - as they journey toward the fabled 13th colony, Earth.
- CreatorRockne S. O'BannonStarsBen BrowderClaudia BlackAnthony SimcoeThrown into a distant part of the universe, an Earth astronaut finds himself part of a fugitive alien starship crew.
- CreatorChris CarterStarsDavid DuchovnyGillian AndersonMitch PileggiTwo F.B.I. Agents, Fox Mulder the believer and Dana Scully the skeptic, investigate the strange and unexplained, while hidden forces work to impede their efforts.
- CreatorCarmen FinestraDavid McFadzeanMatt WilliamsStarsTim AllenEarl HindmanTaran Noah SmithThe daily trials and tribulations of Tim "The Tool Man" Taylor, a television show host raising three mischievous boys with help from his loyal co-host, loving wife, and eccentric neighbor.
- CreatorJeff FranklinStarsBob SagetJohn StamosDave CoulierA widowed sportscaster raises his three daughters with assistance from his rock and roll brother-in-law and madcap best friend.
- CreatorAndy BorowitzSusan BorowitzStarsWill SmithJames AveryAlfonso RibeiroA streetwise, poor young man from Philadelphia is sent by his mother to live with his aunt, uncle and cousins in their Bel-Air mansion.
- CreatorDavid X. CohenMatt GroeningStarsBilly WestJohn DiMaggioKatey SagalPhilip J. Fry, a pizza delivery boy, is accidentally frozen in 1999 and thawed out on New Year's Eve 2999.
- CreatorJames L. BrooksMatt GroeningSam SimonStarsDan CastellanetaNancy CartwrightHarry ShearerThe satiric half-hour adventures of a working-class family in the misfit city of Springfield.
- CreatorSeth MacFarlaneDavid ZuckermanStarsAlex BorsteinSeth MacFarlaneSeth GreenIn a wacky Rhode Island town, a dysfunctional family strives to cope with everyday life as they are thrown from one crazy scenario to another.
- CreatorBruno HellerWilliam J. MacDonaldJohn MiliusStarsKevin McKiddRay StevensonPolly WalkerA down-to-earth account of the lives of both illustrious and ordinary Romans set in the last days of the Roman Republic.
- CreatorGerry AndersonStarsTed ShackelfordRob YoungbloodSimone BendixThe alien adventures of former NYPD detective Patrick Brogan, now a lieutenant in the Demeter City Police Department on the planet Altor.
- CreatorRaymond ThompsonStarsKieren HutchisonAndrew RoberttNathaniel LeesWitness the legend of Wilhelm Gorkeit of Tellikon (William Tell), who, as the stories say, shot an apple off of his son's head and led the rebellion to free Switzerland.
- CreatorPeyoStarsDon MessickDanny GoldmanLucille BlissThe Smurfs are tiny blue creatures that live in mushroom houses in a peaceful forest. They repeatedly try to outwit Gargamel, an evil sorcerer, his apprentice, Scruple, and his mangy cat, Azrael.