Trama

An assassin teams up with a woman to help her find her father and uncover the mysteries of her ancestry.

HITMAN: AGENT 47 centers on an elite assassin who was genetically engineered from conception to be the perfect killing machine, and is known only by the last two digits on the barcode tattooed on the back of his neck. He is the culmination of decades of research and forty-six earlier Agent clones -- endowing him with unprecedented strength, speed, stamina and intelligence. His latest target is a mega-corporation that plans to unlock the secret of Agent 47's past to create an army of killers whose powers surpass even his own. Teaming up with a young woman who may hold the secret to overcoming their powerful and clandestine enemies, 47 confronts stunning revelations about his own origins and squares off in an epic battle with his deadliest foe.—20th Century Fox

Genetically engineered from conception to be the perfect killing machine, he's the culmination of decades of research, endowed with unprecedented strength, speed, stamina and intelligence. Known only as Agent 47 (Rupert Friend), his latest target is a corporation that plans to unlock the secret of his past to create an army of killers even more powerful than him. With help from a young woman, the elite assassin confronts revelations about his own origins in an epic battle with his deadliest foe.

Agent 47 (Rupert Friend), known only by the bar code tattoo on his neck, is an elite international assassin. Engineered to be an unstoppable killing machine, 47 is contracted by a covert organization to assassinate high-profile targets on a global scale. He's given the assignment to kill the leader of a crime syndicate who wishes to unlock the secrets behind 47's powers and harness that information into an army of highly skilled hit men. As 47 races to complete his mission, new information emerges about his origins and sparks a race against time as the agent is hunted for the secrets behind his skills..

Decades ago, Dr. Piotr Litvenko (Ciarán Hinds) was the head of a program to create clone soldiers, "perfect assassins" with enhanced strength, intelligence, and reflexes, and the inability to feel emotions like guilt or remorse. After having a crisis of conscience, Litvenko disappeared, leaving behind his daughter Katia. The government shut the program down & all surviving agents started to drift. Many people tried to re-start the program, but couldn't as modified agents kept dying. So, eventually the task became to locate Litvenko, who could restart the program. An ex-agent Agent 47 tracks down the official in charge of finding Litvenko & eliminates his entire team. He gets Katia's latest information from the official before killing him. It is clear that Agent 47 wants to eliminate Katia, but not clear why. Meanwhile, the eliminated official was being tracked by an organization called the "Syndicate International", who learn of his assassination & deploy assets to find Katia before Agent 47 does.

Years later Katia, now adult, (Hannah Ware) lives in Berlin. She works tirelessly to find her father and is plagued by overwhelming anxiety and an acute awareness of everything around her, even being able to see and hear things well outside a person's normal sensory radius. Katia is approached at a subway station by a man calling himself John Smith (Zachary Quinto). He tells her that Agent 47 (Rupert Friend) is on his way to kill her, and offers her protection, while alluding that he has information about her father. 47 finds and attacks the pair, who are able to escape, but not before 47 grazes Katia's arm with a sniper bullet. Smith tells Katia that Agent 47 is trying to find Litvenko as his employers want to restart the Agent program but can't do it without Litvenko & they believe Katia is the key to finding him.

Smith and Katia hide out in a hotel room where the former explains that he is an operative for a corporation known as Syndicate International, and Katia shows him her map of clues to finding her father. Katia asks John to tell her whatever he knows about her father. John responds with Litvenko's age, medical condition (rheumatoid arthritis) and that he speaks several different languages - including Hindi. And also, that he has stage 3 lung cancer. With these facts, Katia figures out that her dad would be living in a country which has a warm climate where orchids can grow, has Tamil as one of its official languages and with advanced medical treatments available. Just as she is about to determine the country, 47 bursts through the door, shoots Smith in the chest, and knocks Katia unconscious. Elsewhere, 47's handler Diana (Angelababy) contacts another Agent with a contract.

Once Katia awakens, 47 explains to her that she too, is an Agent, only Katia is more advanced than even 47 himself (he even explains that her real name is "Quatre-Vingt-Dix"; which is French for "90"). He shows her how to use her heightened senses in combat, as the two fight against Syndicate forces. Agent 47 tells Katia that they both were part of the same program designed by her father.

They are confronted by Smith, who reveals to have a genetically engineered internal body armor, allowing him to have survived being shot by 47. Despite all these, Katia is not all pleased for being chosen to be a killing machine. Smith demands to know Litvenko's location. After a brief fight, 47 and Katia manage to escape. Katia makes 47 promise that he won't harm her father and finally reveal's Litvenko's location: Singapore. 47 says that Smith is an experiment of the Syndicate, who is trying to create more super soldiers for their private army, but cant go beyond a point without Litvenko's help & hence are desperate to find him.

Once there, they find Litvenko, who frequently needs an inhaler to breathe. He apologizes to Katia for abandoning her, saying that he only wanted to keep her safe. He refers to 47 as her "brother", saying that he had left her with family after all. Just then, Syndicate soldiers attack the group, and they are forced to flee. During the escape, Litvenko is captured by the Syndicate but not before being slipped an explosive-rigged inhaler by 47.

At Syndicate International headquarters, Smith tortures Litvenko under the supervision of Syndicate director Antoine LeClerq (Thomas Kretschmann). Litvenko still refuses to reopen the Agent program. While Katia crashes a helicopter into the building, 47 infiltrates the headquarters disguised as a firefighter. The two fight their way through Syndicate security forces, and 47 is once again confronted by Smith. With Smith being impervious to bullets, 47 defeats Smith by electrocuting him. On the rooftop, 47 and Katia fight their way through the last of the Syndicate's security, but not before LeClerq escapes in a helicopter with Litvenko. In mid-air, Litvenko detonates the inhaler given to him by 47, ensuring that the Syndicate will not come after Katia.

47 then calls Diana and confirms his first target (LeClerq) has been eliminated. When Diana asks about the second target (Katia), 47 drops his phone off the side of the building. As the two prepare to leave, they are confronted by Agent 48, an exact look-alike of Agent 47, who tells them "Diana says 'Hello'" before a gun battle begins between them.

A mid-credits scene shows the electrocuted body of Smith, now with white hair and a ghostly pale complexion, as he jolts awake.