- Bartolomeo d'Alviano: You speak French?
- Ezio Auditore Da Firenze: There were a couple of French girls in Firenze...
- Ezio Auditore Da Firenze: You would not believe the things I have seen, Mario.
- Mario Auditore: Then be sure to stay alive that I might hear of them.
- Cesare Borgia: You can't kill me, no man can murder me
- Ezio Auditore Da Firenze: Than I leave you in the hands of fate
- Niccolò Machiavelli: Rodrigo surrounds himself with snakes and murderers. Even his daughter Lucrezia has been sharpened into one of his most artful weapons. But she pales in comparison to the man behind the Villa attack. He is ambitious, ruthless and cruel beyond imagining, the laws of men mean nothing to him. He murdered his own brother to take power. He knows neither danger nor fatigue. Those who do not fall by his sword clamor to join his ranks. The powerful Orsini and Colonna families have been brought to kneel at his feet and the King of France stands at his side.
- Ezio Auditore Da Firenze: Give me his name.
- Niccolò Machiavelli: Cesare, head of the Papal armies. What does he intend to do with this power? What drives the man? That I still do not know. But, Ezio, Cesare has set his sights on all of Italia, and at this rate he will have it.
- Ezio Auditore Da Firenze: Is that admiration I hear in your voice?
- Niccolò Machiavelli: He knows how to exercise his will. A rare virtue in the world today.
- Juno: In the beginning, we set our truths to parchment. To stone. To the memory of men. These proved impermanent things. Cleansed by fire. Cleansed by famine. Cleansed by flood. All the world is innocent once more. Innocent and ignorant.