Chuck and Blair's relationship in Gossip Girl was filled with drama and toxic moments, but also undeniable chemistry and love. The most important relationship milestones and turning points for Chuck and Blair occurred throughout the series, showcasing their growth and feelings for each other. Some of the best episodes focused on Chuck and Blair's relationship, highlighting their intense emotions, conflicts, and their strong bond even when they were apart.

Everything about Gossip Girl was dramatic – in particular the relationship between central characters Chuck and Blair - and the best Chuck and Blair episodes showcase that drama very well. Spanning the show's entire six-season run, their romance was rocky (and admittedly pretty toxic) but addictive for fans to watch unfold through all its highs and lows. Part of the fun of Gossip Girl was seeing these two characters bring out both the best and the worst in one another as they grew up.