Drea de Matteo never was particularly political. Her only partisan statement came via a 2010 music video she directed for Shooter Jenning’s “Summer of Rage” — a not-so-subtle jab at the Bush-Cheney administration’s ever-churning war machine. In 2020, she voted for the first time in her life in the presidential election, casting her ballot for Joe Biden in his bid to replace Donald Trump in the White House. Then, as the Covid pandemic entered its second year, everything came crashing down for “The Sopranos” actress whose Adriana La Cerva provided the sole conscience in a sea of moral degenerates.

“I’m a hippie. I didn’t want to get the vaccine. I wanted to wait it out to see what the outcome was,” she says.

Her family shunned her for being anti-vax. She became persona non grata among the Hollywood set. And her agent, who she considered a friend, dropped her.