The MG-B that Dr. Wheeler drives in the opening scene with a tan interior and a black plastic honeycomb grille switches to an earlier model with a black interior and an all chrome grille (noticeable in the scene where the car will not start). When Dr. Wheeler visits the Jefferson Institute, it has switched back to the MG-B with the tan interior and black grille.
When Mark puts Dr. Wheeler to bed after the chase at the Anatomy Lab, the bed covers change between when she lies down and when she leaves moments later.
[Theatrical version only] In the room where the coma 'patients' are suspended, there are several topless women clearly visible. Not too much later, there is a shot of the guards in the coma room chasing Susan, and the women's breasts are covered. a few minutes after that, in the next shot of the room, the women are topless again.
At around 1:26:47, when Mrs. Emerson tells Norman about the electrical inspection, the numbered blocks in her desktop calendar change between shots.
When Dr. Harris completes an appendectomy, the anesthesiologist reaches for the patient's endotracheal tube, as Dr. Harris begins to turn away. When he completes the turn, the anesthesiologist is seen removing a face mask from the patient. There was no time for the anesthesiologist to remove the tube and replace it with the mask.
Dr. Wheeler sprays a man with a CO² fire extinguisher, causing white frost to form on his upper body. Since it is not a fire retardant powder, the white substance disappears quickly as it melts.
Dark-haired stuntman falling down the stepped aisle of the lecture theatre, in place of fair-haired villain.
When the anesthetist opens Nancy Greenly's right eye to check her pupil, her startle reflex makes her left eyelid move, giving away the fact that she's not unconscious.
After Dr. Wheeler observes Sean Murphy in the comatose state, she records his patient number in her small notebook. But there was no way for her to know that unless she read his chart, which she clearly was not seen doing.
The ambulance driver states that he has to go through the Sumner Tunnel to get to Logan Airport. Since 1961, the tunnel going to Logan has been the Callahan tunnel. The Sumner tunnel has been outbound from the airport since 1962.
Crew and a camera are reflected in the glass as we first see Mrs. Emerson approach Dr. Wheeler.
Dr. Wheeler and Dr. Bellows are walking along a corridor discussing something. A technician must be moving along the floor with a long microphone which can be seen.
At approximately 1:43:07, Dr. Wheeler reaches over and triggers Dr. Bellows' pager, he tells Dr. Harris that he has to answer his page. The shadow of the boom can be seen on the wall behind them (upper left corner). The shadow follows Michael Douglas as he walks out of frame and then the shadow comes back into frame and follows Richard Widmark.