It’s hard to believe, but Cobweb star Lizzy Caplan hasn’t made a full-fledged horror movie until now. The genre is often a rite of passage for younger actors, especially modern-day performers, but surprisingly, the opportunities never came Caplan’s way despite launching her career 24 years ago. She started out with a handful of appearances on Paul Feig and Judd Apatow’s Freaks and Geeks, as well as the latter’s Undeclared, and she first got to know Seth Rogen through both of the aforementioned comedic projects. Oddly enough, Rogen’s production company, Point Grey, would bring her Chris Thomas Devlin’s Cobweb script two decades later.

In 2004, Caplan’s life forever changed by way of her breakout performance as the witty and brash Janis Ian in Tina Fey and Mark Waters’ now-classic comedy, Mean Girls. So, besides having an aversion to horror movies, Caplan tends to believe that...