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Shaun Murphy, a young surgeon with autism and Savant syndrome, is recruited into the surgical unit of a prestigious hospital.

A conspiracy theorist questions Dr. Marcus Andrews; Dr. Claire Browne treats a woman whose inability to feel pain is threatening both her marriage and her life; Dr. Shaun Murphy and Dr. Aaron Glassman each face crises in their romantic relationships.

Dr. Marcus Andrews vows to help a good Samaritan who was injured while stopping a sexual assault; Dr. Audrey Lim faces a difficult decision when a young patient's parents suspect that Dr. Neil Melendez made a mistake.

Dr. Claire Browne faces complications at home and work as she prepares to lead her first surgery; the staff must treat a fisherman's injuries without damaging his prize catch.

While performing his first solo surgery, Dr. Shaun Murphy alienates a nurse, which puts his residency in jeopardy. Also, Dr. Neil Melendez disagrees with Dr. Audrey Lim on a risky surgery, and Dr. Claire Brown spirals into self-destructive behaviors, causing negative ramifications in the workplace.

Dr. Andrews questions whether Shaun is really ready for his first surgery; Dr. Brown and Dr. Reznick have a patient whose diagnosis has them doubting his story.

Shaun visits his father on his deathbed and the reunion's results are unexpected. Claire addresses her grief. An NFL player needs treatment.

Carly's attempts at increasing her intimacy with Shaun are becoming more of a frustration than either of them expected. Meanwhile, Lim and Melendez struggle in their relationship as they work to separate their work from their personal life.

Dr. Shaun Murphy's unique ability to relate to a patient isolated by an immune deficiency yields an unexpected result; a 12-year-old patient is about to become blind; tension builds between Dr. Neil Melendez and Dr. Audrey Lim.

Shaun is ready for the next step in his relationship with Carly. A young woman must decide on a life saving procedure that might destroy her marriage.

Shaun opens up with Aaron about his feelings towards Lea.

After Shaun treats a famous patient, he deals with unwanted attention. Carly's efforts to separate Shaun from Lea are challenged.

Shaun, Morgan, and Audrey treat a 25-yo runner with severe swelling, Carly determines a cause and joins the case. Meanwhile, Alex, Claire, and Neil treat two 16-yo cancer patients who are dating. Shaun and Carly also work on intimacy.

A terminal patient is determined to live life to the fullest in his final months. Dr. Reznik must confront her relationship with her mother when she asks Dr. Glassman for a third opinion.

Despite everyone else's doubts, Shaun is hopeful that Carly is truly fine with his friendship with Lea; the team treats a young boy born without a fully formed trachea who may be a good candidate for an experimental procedure.

Dr. Murphy becomes obsessed with performing an autopsy on a Jane Doe, which challenges his relationships at the hospital; a male college student has a mysterious split personality disorder.

A patient with a mysterious and undiagnosed illness that has baffled other doctors for years forces Dr. Shaun Murphy and the team to take some big risks. Meanwhile, Dr. Claire Brown and Dr. Neil Melendez continue to cautiously navigate their feelings for each other as colleagues and friends

Shaun is having difficulty getting over Lea. Claire sorts through her feelings for Dash. Morgan makes a decision about her future. Neil's team works on a man with a brain stem abnormality. Dr. Lim and Dr. Andrews clash over treatment for a man with double arm injuries.

In the first episode of the two-part Season 3 finale, St. Bonaventure Hospital is on high alert after a massive earthquake hits San Jose.

Doctors work against time and their own personal safety to save the lives of those around them.

Lea and Shaun's new relationship will become tested. Park gets ready to move back to Phoenix. Morgan puts herself and several members of the staff in danger. Claire continues to work through her grief from the death of Melendez.

Lim tasks Shaun, Claire and Park with mentoring the top first-year resident contenders. Andrews discuss a difficult surgery scheduled for a minor. Shaun inadvertently insults Lea. Morgan seeks out Claire and Lim's help on a consult.

Shaun has a hard time balancing his fears and concerns about potentially jeopardizing Lea's health and wanting to be with the woman he loves. Claire looks for a way to grieve Melendez's death. Park and Mia discuss their future together.

Morgan and Shaun's pregnant patient with twins has pain, forcing the doctors to grapple with a decision no one wants to make; Shaun asks Lea to move back in despite her reservations.