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- Physician and genetics researcher, Jérôme Lejeune acquired an international reputation in 1958 when he discovered the Trisomy 21, cause of Down Syndrome. He hoped his discovery would change the way people looked at children with Down Syndrome, who came by hundreds to his medical consultations. He had only one obsession : to find someday a cure. The meteoric rise of this young French scientist will be be stopped in a flash in 1969. While receiving the William Allen Award in San Francisco, the highest award in genetics, he delivered a speech defending the human dignity of the embryo, causing an earthquake in the scientific sphere. A few months before, he realized that his discovery would be used against his convictions, by opening the door to abortion of embryos with genetic abnormalities. Who was Jérôme Lejeune? A great scientist or a man of faith ? Nowadays what is the state of research on Trisomy 21, in which he had placed so much hope? 20 years after his death, the director François Lespes wondered about this man's complex personality, who had such an extraordinary fate. « Jerome Lejeune - To the least of these my brothers & sisters » is investigating on the man of science and beliefs, from Paris to Indianapolis, from friends to confrères, from supporters to detractors.
- Two worlds colliding for the best. The children of Phnom Penh scavenging the dump-site to survive and a recently retired couple discovering Cambodia. This is the extraordinary human story of Christian and Marie France and how they changed the lives of more than 10,000 kids over 20 years. For a Child Smile is born.
- Leila Mustapha is Kurdish and Syrian. Her fight is Raqqa, the former capital of the Islamic state of three hundred thousand inhabitants, reduced to a field of ruin after the war. An engineer by training, mayor at just 30 years old, immersed in a human world, her mission is to rebuild her city, to reconcile, and to establish democracy there. An extraordinary mission. A French writer crosses Iraq and Syria to meet her. In this still dangerous city, she has 9 days to live with Leila and tell her story in a book.
- Israelians musicians and Palestinians are invited to tour in France. Each of the 14 concerts are a huge success... But backstage, things are complicated.
- Adolescents from Northern and Francophone Africa leave their tiny villages, temporarily or for good, and land on French territory. Called 'suitcase children,' they are thrown into often unstable families. They are still minors, and the French educational system is required to accept them -- even if they're in the country illegally. They must be brought up to speed before being integrated into general or specific areas of study. This is a year where they must find their bearings, adapt to French culture and determine what their future will be.