After claiming to pose as Ted Danson online, Peggy reveals that she has learned Khan is manic depressive. This fact is explored at length in the very last episode aired, Just Another Manic Kahn-Day (2010).
On MySpace, Donna lists her favourite musicians as Willie Nelson, Chuck Mangione, Tammy Wynette, Green Day, Ani DiFranco, Dwight Yoakam, Clint Black, The Chicks, Randy Travis, Brooks & Dunn, Charlie Daniels, Wynonna Judd, Vince Gill, James Brown, Snoop Dogg, No Doubt, Kid Rock, KISS, George Strait, Travis Tritt and Tom Petty. With the exception of Brown, all of them guest starred on the series as either themselves or fictional characters. Most notably, Petty provided the voice of Lucky in 28 episodes from 2004 to 2009.
From 2005 to 2009, MySpace was the largest social networking site in the world, until being overtaken by Facebook. Since then, its popularity has decreased. In October 2016, Myspace (now spelled with a lower case "s") was ranked 2,154 by total Web traffic, and 1,522 In the United States. By 2019, it had only 7 million visitors per month compared to its peak number of 115 million visitors in April 2008.
The last vocal appearance of Roger "Booda" Sack, who was first voiced by Chris Rock and voiced by Phil LaMarr for the rest of the series.
Peggy poses as Ted Danson on MySpace. Danson previously played Tom Hammond in The Accidental Terrorist (2008).