This is Iglesias' second bachata song after "Cuando Me Enamoro".
At the Latin Grammy Awards of 2014, the song received a nomination for Best Tropical Song.
The video has been viewed over 522 million times.
Loco debuted on Billboard Hot 100 chart at number 87 and peaked at number 80, becoming Enrique's highest-charting Spanish song on the chart at the time.
The song debuted in Spain at number 22.