- In autumn 2006, she broke her hip, requiring some of her shots had to be filmed sitting down on Scrubs (2001). This is most noticeable in the episode My Musical (2007), where she was filmed sitting during most of the episode, except with the song "Dominican", which was filmed five weeks later than the rest of the show when she had fully healed.
- Has a daughter, Leila Rey Valencia (b. November 27, 2009), with her boyfriend George Valencia.
- Fraternal twin sister of Joselin Reyes.
- Won the 2006 Outstanding Actress on a TV Show ALMA award for her role in Scrubs (2001).
- She became interested in acting while attending Hunter College in Manhattan, New York. She is a founding member of the Labyrinth Theatre Company, a multi-cultural acting space in Manhattan.
- One of four daughters, three of whom are actors.
- Older sister of Fidias Reyes.
- Has been in "NYPD Blue" along with 3 other members of the Scrubs (2001) cast - Sam Lloyd, Ken Jenkins, and Neil Flynn.
- Has played a nurse in both the television series Scrubs (2001) and the film Bringing Out the Dead (1999).
- In two years, Reyes was in both a movie called Little Girl Lost: The Delimar Vera Story and an episode of Castle titled "Little Girl Lost.".
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