- She has a soul/funk/rock band, "School Boy Crush", that plays around Los Angeles, and is in the middle of writing an album.
- She has been doing professional theatre since she was 12 years old.
- At age 6, she sang at Bar-Mitzvah parties.
- Her parents are both from Ashkenazi Jewish families (from Lithuania, Poland, Ukraine, Romania, Russia, and England).
- Jaime earned a living as a jazz singer before getting her role on General Hospital (1963).
- She studied acting at the prestigious Interlochen Music and Arts Camp, and for many years held the lead in the summer play performances.
- In August 2013, Newman was nine months pregnant with a baby girl when she went into labor. She arrived to the maternity ward at Cedars Sinai where it was found out that her baby had no heartbeat, and she lost her girl in a stillbirth. After subsequent years of IVF treatments, and four more miscarriages, she turned to surrogacy and welcomed daughters Alma and Mila in September 2018 and October 2019, respectively.
- She formed her own production company in Detroit called "Apollo Productions", where she produced three plays over two years.
- Mother, with husband Guy Nattiv, of daughters Alma Ness Newman Nattiv (b. September 18, 2018) and Mila Nico Newman Nattiv (b. October 3, 2019). Both girls were born through the help of surrogate mother.
- Is a redhead.
- She went to college at Boston University & Northwestern University.
- She and her husband, Guy Nattiv, won their first Academy Award on February 24, 2019. They received the Oscar for their short film Skin (2018), a 20-minute elegy about racism in America.
- Daughter Alma's middle name Ness means "miracle" in Hebrew.
- Married Guy Nattiv on her 34th birthday that on April 2, 2012.
- Studied directing at Northwestern University.
- In 2003 she starred opposite David Schwimmer and Jonathan Silverman in the premiere of Roger Kumble's hit play "Turnaround". Was the only female in the cast.
- She is a graduate of the Cranbrook-Kingswood School in Bloomfield, Michigan - the same high school of which Selma Blair and Elizabeth Berkley are alumnae.
- A second daughter, Mila Nico Newman Nattiv, was born October 3, 2018 via surrogate, weighing 1lb 9oz.
- She has starred in two plays by Neil LaBute at The Geffen Playhouse in Los Angeles. "Fat Pig", directed Jo Bonney, and "Some Girls", directed by Neil LaBute.
- Daughter Mila was born 15 weeks earlier.
- Cousin of actor Ben Kurland.
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