Zach Galifianakis and Ed Pearce in Muppets Most Wanted (2014)

Michael Keaton and Zach Galifianakis in Birdman or (The Unexpected Virtue of Ignorance) (2014)

Jerry Seinfeld and Zach Galifianakis in Comedians in Cars Getting Coffee (2012)

Jerry Seinfeld, Wayne Knight, and Zach Galifianakis in Between Two Ferns with Zach Galifianakis (2008)

Zach Galifianakis in Bored to Death (2009)

Reese Witherspoon, Oprah Winfrey, Zach Galifianakis, Mindy Kaling, Storm Reid, Levi Miller, and Deric McCabe in A Wrinkle in Time (2018)

Conan O'Brien and Zach Galifianakis in Conan (2010)

Conan O'Brien, Zach Galifianakis, and Andy Richter in Conan (2010)

Zach Galifianakis and Tessa Thompson in The Late Late Show with James Corden (2015)

Zach Galifianakis in Saturday Night Live (1975)

Zach Galifianakis in A Wrinkle in Time (2018)

Zach Galifianakis in Birdman or (The Unexpected Virtue of Ignorance) (2014)

Zach Galifianakis in Keeping Up with the Joneses (2016)

Zach Galifianakis and Sarah Snook in The Beanie Bubble (2023)

Elizabeth Banks and Zach Galifianakis in The Beanie Bubble (2023)

Zach Galifianakis in Between Two Ferns: The Movie (2019)

Zach Galifianakis, Ryan Gaul, Lauren Lapkus, and Jiavani in Between Two Ferns: The Movie (2019)

Bradley Cooper, Zach Galifianakis, and Ed Helms in The Hangover (2009)

Zach Galifianakis, A.D. Miles, Andrea Savage, and Matt Walsh in Dog Bites Man (2006)