- I learned to fall down early in life - I was like six - because I realized it was a way to make girls laugh.
- [on originating the show 'Mr. Sunshine'] Some of it is based on me. I like to think I'm a little less selfish than this character, but at times in my life I certainly have been that way. I've been accused of not really paying attention to a sentence unless my name comes up in it twice.
- When I did 'Studio 60 on the Sunset Strip' I would look over and see Aaron Sorkin pacing around in the corner of the stage, mumbling to himself. I thought, Well, he's crazy. And then I realized what he was actually doing was playing out the next week's scenes as he was writing them. And that was intriguing to me. So now I've become one of the people that mumbles in the corner of the room.
- [on his sports-based series 'Go On'] Whenever I come across a famous athlete, I'm shameless. I'll just ask them to be on the show. To my face they've all said yes so far.
- I gravitate towards sort of broken characters who try to be better people.
- [With all my roles] I just keep playing myself.
- [In high school] there was a group of cool kids and a group of really dorky kids, and I was probably the coolest of the really dorky kids.
- I need a woman to have a quirky sense of humor. There's a bunch of jokes I use, and if she doesn't get them, she's probably not for me.
- My favorite actor was, is, Michael Keaton. Certainly growing up, in the movie Night Shift (1982) he did something brand new that I hadn't seen before that we all steal from now. And then it was in 1987 he did the movie Clean and Sober (1988) and Beetlejuice (1988) in the same year, and that was when I said, "Wow, that's what I want to do."
- [2022] The best thing about me, bar none, is that if an alcoholic or drug addict comes up to me and says, 'Will you help me?' I can say yes and follow up and do it. When I die, I don't want 'Friends' to be the first thing that's mentioned. I want that to be the first thing that's mentioned. And I'm gonna live the rest of my life proving that.
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