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A close-knit group of housewives reside in Wisteria Lane. It may appear to be a seemingly perfect neighborhood but it hides many secrets, crimes, forbidden romances and domestic struggles.

An anthology series that follows three women in different decades all living in the same house, as they deal with infidelity and betrayals in their marriages.

A stranger arrives in the small town of Hallelujah, Tenn., which is being torn apart by the forces of good and evil.

Fed up with men,two thirty-something gals decide to take matters into their own hands. During a booze-fueled night of war-stories, they have an epiphany -switch teams.

On Valentine's Day, Edie thinks that Karl is going to pop the question after she finds an engagement ring and prenuptial agreement in his briefcase, but Karl is actually trying to get Susan to marry him, instead, so she can get insurance for her upcoming surgery. Gabrielle and Carlos learn she is highly unable to conceive a child again because of complications caused from her recent miscarriage. At the same time, Carlos learns more about the tension-filled relationship between Gabrielle and her estranged, gold-digging mother Lucia, when she drops by for a visit. Also, Bree's problem with alcohol intensifies with the notice of Lynette after Bree babysits her children for the day in which she passes out, and the twins wander around town.

Gabrielle goes to great lengths to hide her affair with her gardener, John; Lynette tries to discipline her twin boys with tough love; Bree and Rex try marriage counseling.

Susan is miffed when Mike gets an unexpected house guest named Kendra; Andrew gets into a serious car accident that puts Mama Solis in the hospital; Mr. Shaw comes closer to solving who was blackmailing Mary Alice.

Susan's mother pays an unexpected visit; Gabrielle faces Carlos' wrath; While babysitting Lynette's children, Bree punishes the twins for misbehaving; Felicia gets closer to Zach, revealing more disturbing details about his family.

Lynette and Tom find a like-minded couple to watch their kids, Susan strikes up a romance with her ex-husband, and Gabby tries to hide her pregnancy.

Bree finds out that Rex is cheating, and he has a heart attack; Susan plans to take her relationship with Mike to the next level; Lynette, suspicious of her new nanny Claire, decides to secretly videotape her.

A break-in on Wisteria Lane leaves the neighbors feeling vulnerable; After Rex takes the kids away for the weekend, Bree finds herself bonding with Zach; Gabrielle takes drastic measures to keep Juanita oblivious to her secret.

Bree has to deal with George's death, Lynette tries to get daycare at work, Susan has problems with her father's wife, Gabrielle fights for her husband and the Applewhites get Caleb back.

Gabrielle plans a big party to bid farewell to Carlos and begins to suspect she's pregnant; George Williams returns, much to Rex's displeasure; Lynette learns Tom's old girlfriend, has been hired at his firm again; Susan and Julie encounter strange behavior from the Young family.

Susan and Mike decide to move in together; Lynette takes steps to make sure Annabel doesn't come between her and Tom; Bree comes to a realization about George; Carlos' legal problems take a turn for the worse; Martha Huber's journal falls into the hands of Susan and Julie.

Bree and Rex cover up Andrew's accident; Susan grows suspicious of Mike's real reason for moving to Wisteria Lane; Gabrielle questions the priest, who John confessed her adulterous affair to.

Susan tries to get Paul Young arrested, while her mother pays another visit; Carlos continues serving his jail sentence, while Gabrielle tries to free him, but his lawyer refuses to represent him; Bree gets a bad rash every time she tries to be intimate with George; Lynette gets into a minor argument with Tom over her purchase of a number of very expensive business suits to impress Nina.

Mike is questioned in Martha's murder; Justin tries to blackmail Gabrielle; Tom wants a big promotion, but Lynette fears she would be left alone with the kids even more; Julie learns of Zack's dark side.

Lynette learns that no good deed goes unpunished when she befriends Mrs. McClusky; Susan's mother decides to try to jump-start her and her daughter's love lives; Bree forces Andrew to talk to the family priest about his conflicted sexuality.

Susan looks forward to a romantic date with Mike until she learns a surprising fact; Lynette's neighbor accuses her twins of thievery; Bree learns of Rex's sexual needs; Gabrielle's work adventures continue.

Edie organizes a neighborhood search for Mrs. Huber, just as her sister arrives on Wisteria Lane; Bree agrees to a separation and asks an attractive pharmacist on a date; Susan's ex-husband, Karl, suddenly returns for a visit; Lynette's fears Tom is attracted to their nanny.

Lynette's son has an imaginary friend, George and Andrew fight over Bree's attention, Susan struggles with the Zach situation, and Gabby has lawyer problems.

Lynette goes back to work; Gabrielle struggles with her pregnancy and Carlos in jail; Bree deals with Rex's death; Susan learns more about Mike's past.

Gabrielle kisses Tom; Andrew tries to blackmail Bree; Mike tries to spend a little time with Zach, which angers Paul.