- Frank's caught wildlife in the Brazilian jungle incl. a 400 lbs. white jaguar. He ships it on the same ship as an arrested assassin. The assassin breaks free and frees the animals.
- A big-game hunter for zoos has booked passage on a Latin American shipping freighter with a fresh haul of exotic and deadly animals from the Amazon, including a rare white Jaguar - along with a political assassin being extradited to the U.S in secret. Two days into the journey, the assassin escapes and releases the captive animals, throwing the ship into chaos.—anonymous
- The hunter Frank Walsh captures and steals wild animals from the Floresta Amazônica and smuggles them in a ship. Meanwhile, an American agency brings the skilled agent Richard Loffler, who was trained to be an assassin, together with a security team and a doctor to be transported to the USA in the same vessel. Along the journey, Loffler escapes and releases the animals to bring chaos on board.—Claudio Carvalho, Rio de Janeiro, Brazil
- Frank Walsh (Nicolas Cage), a big-game hunter for zoos has booked passage on a ship, where a dangerous criminal is also imprisoned. Frank has just captured a white jaguar, whom the locals believe to be an evil spirit whom they offer human sacrifices to keep their village safe.
As Frank preps to transport his jaguar across the ocean to the US, he finds that criminal Richard Loffler (Kevin Durand) is also being transported on the same ship, escorted by FBI agents. Richard has killed a US Senator and is being arrested for crimes against humanity. Dr. Ellen Taylor (Famke Janssen) is a neurologist and travels with Richard to monitor his mental health. Richard is ex-Navy himself and went rogue. Ellen tells Frank (at lunch in the ship cafeteria) that Richard has a brain condition that can kill him if the atmospheric pressure changes. That is why flying him to the US is not an option.
The white jaguar is worth a million dollars to Frank. Frank intends to auction it to the highest bidder, but Ellen wants him to turn the cat over to the endangered species bureau. Inevitably, Richard fakes a seizure, kills his guards, and escapes captivity. John Ringer (LaMonica Garrett) is in charge of the FBI team and launches his team to find Richard. Richard has let loose some of the vicious monkeys from Frank's hold, who end up killing some of the ship's crew. Richard has a radio & uses that to communicate with Frank. Frank tells him that he was military himself and served as a mechanic for 4 years. Richard says he did not like when the military trained him to be an assassin for life and then one day told him to leave everything and come home.
Frank finds that Richard has let loose most of his animals, including 2 venomous snakes. Richard has also stopped the water pumps on the ship. The jaguar & the snake end up killing more men on the ship. Richard launches the lifeboats. He takes control of the command section of the ship, keys in coordinates, and then destroys all controls. Finally, Richard attacks and kills John Ringer and most of his team. Frank still doesn't want to abandon ship as he believes a white jaguar is a once-in-a-lifetime catch and also this is his only chance since he doesn't have permits to transport any of them.
Turns out FBI man Paul Freed (Michael Imperioli) is working from the inside for Richard and helps him stay ahead in the game by feeding him vital intel on FBI tactics and next steps. The remaining engineers on the ship shut down the engines to stop Richard from escaping to the Caribbean Islands (the new course he had set into the ship's computers).
Richard uses the radio to impersonate John Ringer and call in the Coast Guard to mount a rescue. Frank finds Richard, who now has Ellen in his custody, he is about to kill Richard when Paul intervenes. Richard tells Frank that Paul is NSA who hired Richard to kill NSA targets in South America. He now has enough intel to tie the drug cartels directly to NSA officials, which is why Paul wants him alive, so he can profit from that Info. Richard kills Paul, but both Frank and Richard are injured.
Frank stuns Richard with a neurotoxin dart, captures him in a noose and lets loose the white jaguar to eat him alive. He rescues Ellen. As the Coast Guard reaches the ship, the captain asks Frank about the paperwork on his animals. Ellen lies that Richard destroyed Frank's paperwork and she saw that everything was in order.
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