The Campaign for North Africa, which Sheldon brings over to try to play with Bernadette, is a real-life game that was released in 1978; it is considered one of the most difficult and longest games ever to be played. It's also considered a collector's item and a cult favorite to hardcore gamers. It is famous for the "Pasta rule", which requires for the Italians to consume more water for boiling their pasta.
Having sexual intercourse in order to initiate labor is a real practice. Intercourse (especially orgasm) releases the hormone oxytocin, which can induce contractions in the uterus. Furthermore, male semen contains hormones called prostaglandins that can cause the cervix to start dilating. Although this method isn't exactly proven effective, many doctors and midwives have a positive attitude towards it, since there are no negative consequences as long as the mother's water has not broken.
This is one of the few episodes to feature only the main cast and no guests (not even Stuart), but since there are scenes set at CalTech with many extras, it probably wouldn't meet the criteria of a "bottle episode" (episodes made with limited cast and few sets, often to save money).
This is the second time that Sheldon suggests to "rent" Penny's womb in order to procreate with Amy, after The Robotic Manipulation (2010).
Ozymandias, as suggested by Sheldon as a name for a baby, would hold a nice additional meaning. He was an Egyptian Pharaoh (also known as Ramesses II) who was the subject of Percy Bysshe Shelley's poem 'Ozymandias' (known for the famous phrase "Look on my works, ye Mighty, and despair!"), but it is also the name of an important character from the popular Watchmen comic, and its adaptation, Watchmen (2009).