While undercover, Lucifer and Pierce choose the names Mark and Luke, both of whom are names with a Gospel book attributed to them.
While in conversation as they try to figure out how Cain may die, Lucifer states "Everyone has their Kryptonite!" Tom Welling played Clark Kent in the long running show Smallville (2001). Based on Tom Welling's reaction to the line, it's possible he didn't know it was coming.
In addition to the Gospel connection, while undercover Marcus/Cain chooses to go by Mark, as in "Mark of Cain," and Lucifer chooses Luke, which means "light" or "the bright one," in line with both him being the Lightbringer and with him choosing to name his nightclub Lux, which also means "light."