- Lacy Westman: You know math teachers... you get'em drunk and next thing you know they're playing spin the compass and hide the protractor.
- Carine: I like what you've done with the place.
- Bill Palet: Yes. Thank you. I think it's called negligent minimalism.
- Dr. Rollens: No one is Replaceable, that doesn't mean someone else can't play a special role in your life.
- Dr. Rollens: I find that grieving spouses usually fall into one of two groups. One describes their loved one as someone who filled a void in them. The other describes them as someone who added a dimension to the person they already were. Which would you say best describes you?
- Bill Palet: Both.
- Lacy Westman: I'm sure you've heard I'm some kind of freak slut basket-case, but I'm afraid any hope you had of us having wild gymnastic sex are destined to be frustrated.
- Wes: Gotcha!
- Nancy Abernac: [quoting Jeanie] Look, you're bound to have better luck at the Natural History Museum. They have a few gals in their Neanderthal exhibit, who would think you're the greatest thing that walks upright and talks at the same time.
- Wes: Leaning on people really hasn't worked out all that well so far, so... just not gonna do it anymore.
- Dr. Rollens: [starting Bill's treatment] Neurons that fire together, wire together. So when we're happy, the neurons in our brain align in a way that tends to sustain that feeling of well being. The same idea also applies to depression. Like what you'd expect during a period of grief.
- Raffi Akka: Okay so what's up with that Lacy Westman girl? The Princess of Darkness.
- Wes: You mean my future wife?
- Raffi Akka: Dude, she would have sex with you and then eat your head.
- [first lines]
- Bill Palet: [wanders into his room in the middle of the night]
- Wes: Dad?
- Bill Palet: I can't stay here anymore.
- Paul Abernac: You want to do better don't you?
- Wes: Doesn't matter.
- Paul Abernac: It only matters if it matters to you.