Betty White guest stars as an intern,along with Brian Klugman. Ms.White was long time friends with Brian's uncle and aunt, Jack Klugman and Brett Sommers. White appeared on The Odd Couple with Jack, and was a recurring panelist on The Match Game with Brett.
Betty White was 93(!) when she guest starred on this episode.
Tom Lenk also appeared in Buffy the Vampire Slayer (1997) and Angel (1999) alongside David Boreanaz.
Ronde Barber plays an NFL running back in this episode. In reality Ronde played cornerback in the NFL for The Tampa Bay Bucs. However his brother, Tiki Barber, played running back for the New York Giants.