Sam and Dean go by the aliases Agent Cobain and Agent Grohl when they meet the girl named Janet Novoselic. This is a reference to the band Nirvana as frontman Kurt Cobain, drummer Dave Grohl and bassist Krist Novoselic.
The country song about honoring a deceased family member by driving their truck is "I Drive Your Truck" by Lee Brice.
Dean asks Janet, "So Trini and everything else in the truck just went all Christine (1983)?" "Christine" is a horror novel by Stephen King published in 1983, the same year John Carpenter directed the eponymous movie about a possessed car.
When Dean and Sam are trying to find out how to get of rid the ghost. Dean mentions the ghost might be like Shocker. Shocker (1989) star Mitch Pileggi who also played their maternal grandfather Samuel Campbell in seasons 4 and 6.
Barbara Kottmeier, who plays Corey Silver, also appeared in an earlier episode of "Supernatural", episode #4.8, Wishful Thinking (2008) (as "Candace Armstrong").