Amanda Schull plays Dr. Cassandra Railly. (In the movie Twelve Monkeys, the character was called Dr. Kathryn Railly.) In Greek mythology, Apollo gave Cassandra the power of prophecy in order to seduce her. When she refused him, he added a curse of never being believed. Like her namesake, Dr. Cassandra Railly knows the future, but nobody believes her.
At the end of this episode you will see the J.D. Peoples Psychiatric Treatment Center where Jennifer resides. The name J.D. peoples refers to Janet and David Peoples, who wrote the screenplay for the original film ' 12 Monkeys '.
Aaron Stanford (James Cole) and fellow actor Noah Bean (Aaron Marker) have previously acted together on the TV show 'Nikita' with Maggie Q. Amanda Schull (Dr. Cassandra Railly) also made an appearance in an episode.
The episodes original title was to be called "Splinter".
Aaron Stanford (James Cole) and Zeljko Ivanek (Leland Goines) have appeared in the X-Men movie franchise: Aaron appeared in both 'X-Men 2' and 'X-Men: The Last Stand' as John Allerdyce/Pyro, while Zeliko appeared in 'X-Men: Apocalypse' as a Pentagon Scientist.