Vince Gilligan has confirmed that the desert in which Jimmy (Bob Odenkirk) negotiates with Tuco (Raymond Cruz) is the same spot where Walter White (Bryan Cranston) gives his "Say My Name" speech.
Tuco Salamanca (Raymond Cruz) is seen looking after his grandmother; in Breaking Bad (2008) he was seen looking after his uncle. In both episodes, he is shown preparing food for the relative he's tending.
When Jimmy (Bob Odenkirk) is caught looking at himself in the bathroom mirror saying, "It's showtime!" he insists, "Hey, it's in a movie!" He is referring to Bob Fosse's film All That Jazz (1979).
This episode marks the earliest chronological appearance of Gonzo (Jesus Jr.) and No-Doze (Cesar Garcia), who first appeared in Breaking Bad (2008).
This episode has large implications for Breaking Bad (2008), for instance in Saul's introductory episode, Saul (Bob Odenkirk) is freaking out during Walt (Bryan Cranston) and Jesse (Aaron Paul)'s attempt to intimidate him. What at first seems like Saul simply fearing for his life is actually now Jimmy afraid that Tuco (Raymond Cruz)'s men have decided to finally kill him. He says that whatever they think he did, Ignacio was the real culprit. "Ignacio" is Nacho Varga (Michael Mando)'s real name.