Uzo Aduba (Crazy Eyes)'s character was only meant to appear in the first three episodes. After seeing her performances, the writers and producers made her a recurring character.
Jason Biggs makes a reference to American Pie when Larry mentions 'the webcam horror' and the 'penis shaving incident'.
Deborah Rush (Carol Chapman) and Bill Hoag (Bill Chapman) also worked together on In & Out (1997) as Ava Blazer and a bartender respectively.
Taylor Schilling (Piper Chapman), Kate Mulgrew (Galina 'Red' Reznikov), and Michael Chernus (Cal Chapman) also worked together on Mercy (2009) as Nurse Veronica Callahan, Mrs. Jeannie Flanagan, and Ryan Flanagan respectively.