The flashback scene that shows Dr. Charles' (Matt Ross) son getting kidnapped is an obvious reference to Charles Lindbergh's son getting kidnapped and killed.
When Vivien (Connie Britton) and Ben (Dylan McDermott) pull up to the house, as the camera pans over the front yard, two skeletons can be seen posed in a sexual position over a pumpkin. It is soon revealed that the yard was vandalized.
Chad's (Zachary Quinto) reference to unleashing his and his partner's inner "George and Martha" is a reference to the quarreling couple in Who's Afraid of Virginia Woolf? (1966).
Zachary Quinto and Frances Conroy both appeared in HBO's Six Feet Under.
Kaylee Bryant's from The CW's Legacies first appearance with a speaking role, minus a short according to IMDB