Amber Tamblyn's character, Martha Masters, mentions her father and mother being 19 years apart when discussing happy marriages. This is the same age difference between the actress and her husband, David Cross.
House says, "If you prick us, do we not bleed," a reference to Shylock's monologue in Shakespeare's The Merchant of Venice.
House says, "You look smashing, Miss Moneypenny." Along with Hugh Laurie impersonating Sean Connery, this is a direct reference to the James Bond films. Miss Moneypenny is the secretary to Bond's boss, M, and the two maintain a flirtatious relationship throughout much of the movie series, particularly in the Sean Connery films.
Jesse Spence (Dr. Chase) and Stella Maeve (Kenzie - one of the women Chase met at the wedding) are members of the "Chicago" television shows, Stella in Chicago P.D. (2014) and Jesse in Chicago Fire (2012).