In episode 1 of season 2, Bailey comments that she was the only female intern of her year, but there were other female interns in the room when Webber was doing rounds.
Ellis Grey in the flashback has brown eyes while the Ellis Grey that died had light blue eyes.
Every episode of the show is named after a famous song. "The Time Warp" is a song from The Rocky Horror Picture Show (1975).
Missy Pyle who played Dr. Baylow in Bailey's flashback appeared on an episode of Frasier as a patient. In the same episode T.R. Knight (George O'Malley) also had a role as a patient. Even more, both series (Grey's Anatomy and Frasier) are placed in Seattle.
Gregg Henry also starred in another medical tv series, Chicago Med, as Cardio-thoracic surgeon Dr. David Downey.