Though Hodgins mentions in previous episodes that he has three doctorates, this is the first episode that he reveals what those doctorates are in. Geology, Botany, and Entomology.
Booth's full name is Seeley Joseph Booth. Told to Dr. Sweets as Booth is demonstrating he's fully recovered from his surgery.
In season 3 episode 14, titled The Wannabe in the Weeds (2008), Brennan states that when she was a child her family told her she sung Cyndi Lauper's 'Girl's Just Want to Have Fun' better than Lauper. In this episode Lauper plays Angela's psychic Avalon.
This is the first episode Emily Deschanel and David Boreanaz received credit as full-fledged Producers for the remainder of the series. For seasons 3 & 4 they each was listed as '"Co-Producer" and before that they only had acting credits.
This is the second time Cyndi Lauper has played a psychic. The first being the movie Vibes, starring alongside Jeff Goldbulm.