House says, "29-year-old special ed teacher coughs up blood all over Corky," referring to the TV series Life Goes On (1989-1993), which revolved around the life of Charles "Corky" Thatcher (Chris Burke), a boy with Down syndrome who mainstreamed into regular life.
Another of House's pratfalls. Hugh Laurie did a lot of physical comedy with his partner Stephen Fry and it has been put to good use in the series.