The "pregnancy pact" aspect of this episode's plot was based on a real-life story that broke during the summer of 2008 in Gloucester, Massachusetts, in which 18 teen girls in the same high school became pregnant around the same time (this was over 4 times the previous year's pregnancy rate at that school). The notion that there was a "pact" between the Gloucester girls quickly spread through the media; unlike in this episode, it was never proven conclusively that any or all of the real girls did make a "pregnancy pact."
This marks the first appearance of the character Arastoo Vaziri portrayed by Pej Vahdat. Mr. Vaziri is another one of Dr. Brennan's "squints".
Dr. Sweets (John Francis Daley) interrogates a girl named Alyssa Howland (Kayla Ewell). On the cult hit Freaks and Geeks (1999), Ewell played Maureen, a girl Daley's character, Sam Weir, is infatuated with.
When Mr. Vaziri is describing the three fractures in the victims hand in between the first he says "snap" then "crack" and after the last one Hodgins says "pop". A little play with the Rice Crispies characters snap, crackle, and pop