At around 13:05, Micah is seen playing the piano. Noah Gray-Cabey, the actor that plays Micah, knows how to play piano and has since he was 3 years old. Monica, because of her ability, is all of the sudden able to play simply from observing Micah. This in fact is how Noah learned in real life, by watching his father play. By 4 years old, he was playing with in an orchestra.
First appearance in the series of Kristen Bell playing Elle. She was cast largely after Comic-Con when two of the show's writers were riding on a train and noticed Zachary Quinto and Bell chatting together. Turned out that Quinto and Bell are longtime friends and Bell was already interested in the show.
David Anders (Takezo Kensei/Adam Monroe) & Kristen Bell (Elle Bishop) also worked together on episode 2.11 Fifty Shades of Grey Matter (2016) of iZombie (2015).
Jeanette Brox and Milo Ventimiglia both appeared on Gilmore Girls.