This episode was inspired by Harvard President Lawrence Summers comments in 2005 that gender plays a role in why there are less women in math and science.
The opening Itchy And Scratchy Musical is, in parts, a parody of The Lion King Musical
Bette Nesmith, who invented Liquid Paper, was the mother of Michael Nesmith, the lead guitarist of the 1960s pop-rock band The Monkees.
Liquid Paper was invented by Bette Nesmith Graham (woman), Paper by Tsai Lun (man), Windshield Wipers by Mary Anderson (woman), the car by Nicolas-Joseph Cugnot or Ferdinand Verbiest (both men), Nylon Stockings by Allen Gant Senior (man - Marge is wrong), Rocket Ships by Lieutenant General Henry Shrapnel (man), Suspension Bridges by James Finlay (man), Snow Shoes by Sondre Norheim (man), Pinball Machines by Henry Joseph (man), and no one person invented Constitutional Government or the Renaissance, however women didn't have any power back then, so it's unlikely that any women had a hand in either of them.