Prof. Farnsworth mentions that Mars University was founded in 2636. This is 1000 years after the 1636 founding of the New College, the oldest institution of higher learning in the United States. (In 1639, it was renamed Harvard.)
Much of this episode references to National Lampoon's Animal House (1978). In the film, Delta house was put on double secret probation. In this episode Dean Vernon states that robot house is put on dodeca-tuple secret probation. The Dean was named after John Vernon, who played Wormer.
This is the first episode with alternate opening music. The others are Bender Should Not Be Allowed on TV (2003), Spanish Fry (2003) and Futurama: Into the Wild Green Yonder (2009).
"Transmitido en Martian en SAP". Back in the 90s Secondary Audio Programing was available to provide an additional language track for analog television transmission, often as a near simultaneous translation into Spanish.
Mentholyptus Hall is a spoof on cough drops Hall's Mentholyptus.